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Non-selective voltage-gated ion channel VDAC1

Summary

UniProt ID

Q9Z2L0

Gene Symbol

VDAC
Vdac1

Gene ID

83529

Organism

Rattus norvegicus (Norway rat)

External Links

GlyGen: Q9Z2L0
PubChem: Q9Z2L0
The O-GlcNAc Database: Q9Z2L0
RaftProt: Q9Z2L0
O-GlcNAcAtlas: Q9Z2L0
Re-Glyco: Q9Z2L0

Annotation

Keyword

ATP-binding
Acetylation
Apoptosis
Cell membrane
Direct protein sequencing
Isopeptide bond
Lipid transport
Lipid-binding
Mitochondrion outer membrane
NAD
Phosphoprotein
Porin
Reference proteome
Transmembrane beta strand
Ubl conjugation

Gene Ontology (GO)

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GO Term
mitochondrial outer membrane
plasma membrane
membrane
mitochondrial membrane
protein-containing complex
mitochondrial nucleoid
mitochondrion
synaptic vesicle
membrane raft
presynaptic active zone membrane

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

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GO Term
negative regulation of reactive oxygen species metabolic process
positive regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization
behavioral fear response
neuron-neuron synaptic transmission
learning
monoatomic anion transport
mitochondrial calcium ion transmembrane transport
lipid transport
apoptotic process
chemical synaptic transmission

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GO Term
ceramide binding
monoatomic anion channel activity
calcium channel activity
ATP binding
voltage-gated monoatomic anion channel activity
porin activity
protein kinase binding
phosphatidylcholine binding
oxysterol binding
cholesterol binding

Annotation information from UniProt.

Sequence

MAVPPTYADLGKSARDVFTKGYGFGLIKLDLKTKSENGLEFTSSGSANTETTKVNGSLETKYRWTEYGLTFTEKWNTDNTLGTEITVEDQLARGLKLTFDSSFSPNTGKKNAKIKTGYKREHINLGCDVDFDIAGPSIRGALVLGYEGWLAGYQMNFETSKSRVTQSNFAVGYKTDEFQLHTNVNDGTEFGGSIYQKVNKKLETAVNLAWTAGNSNTRFGIAAKYQVDPDACFSAKVNNSSLIGLGYTQTLKPGIKLTLSALLDGKNVNAGGHKLGLGLEFQA

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites