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Histone deacetylase 6

Summary

UniProt ID

Q9Z2V5

Gene Symbol

Hdac6

Organism

Mus musculus (house mouse)

External Links

GlyGen: Q9Z2V5
PubChem: Q9Z2V5
The O-GlcNAc Database: Q9Z2V5
O-GlcNAcAtlas: Q9Z2V5

Annotation

Keyword

Actin-binding
Cell projection
Chromatin regulator
Cytoskeleton
Hydrolase
Methylation
Nucleus
Phosphoprotein
Reference proteome
Repeat
Repressor
Transcription regulation
Ubl conjugation
Zinc-finger

Gene Ontology (GO)

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GO Term
response to corticosterone
mitochondrion localization
cilium disassembly
parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization
aggresome assembly
cellular response to misfolded protein
cellular response to parathyroid hormone stimulus
tubulin deacetylation
positive regulation of cellular response to oxidative stress
negative regulation of aggrephagy

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GO Term
neuronal cell body
axon cytoplasm
centrosome
microtubule
caveola
perikaryon
aggresome
histone deacetylase complex
microtubule cytoskeleton
cell leading edge

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GO Term
tubulin deacetylase activity
zinc ion binding
tau protein binding
RNA polymerase II cis-regulatory region sequence-specific DNA binding
transcription corepressor binding
actin binding
histone deacetylase activity
microtubule binding
polyubiquitin modification-dependent protein binding
ubiquitin protein ligase binding

Annotation information from UniProt.

Sequence

MTSTGQDSSTRQRKSRHNPQSPLQESSATLKRGGKKCAVPHSSPNLAEVKKKGKMKKLSQPAEEDLVVGLQGLDLNPETRVPVGTGLVFDEQLNDFHCLWDDSFPESPERLHAIREQLILEGLLGRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLAETYDSVYLHPNSYSCACLATGSVLRLVDALMGAEIRNGMAVIRPPGHHAQHNLMDGYCMFNHLAVAARYAQKKHRIQRVLIVDWDVHHGQGTQFIFDQDPSVLYFSIHRYEHGRFWPHLKASNWSTIGFGQGQGYTINVPWNQTGMRDADYIAAFLHILLPVASEFQPQLVLVAAGFDALHGDPKGEMAATPAGFAHLTHLLMGLAGGKLILSLEGGYNLRALAKGVSASLHTLLGDPCPMLESCVVPCASAQTSIYCTLEALEPFWEVLERSVETQEEDEVEEAVLEEEEEEGGWEATALPMDTWPLLQNRTGLVYDEKMMSHCNLWDNHHPETPQRILRIMCHLEEVGLAARCLILPARPALDSELLTCHSAEYVEHLRTTEKMKTRDLHREGANFDSIYICPSTFACAKLATGAACRLVEAVLSGEVLNGIAVVRPPGHHAEPNAACGFCFFNSVAVAARHAQIIAGRALRILIVDWDVHHGNGTQHIFEDDPSVLYVSLHRYDRGTFFPMGDEGASSQVGRDAGIGFTVNVPWNGPRMGDADYLAAWHRLVLPIAYEFNPELVLISAGFDAAQGDPLGGCQVTPEGYAHLTHLLMGLAGGRIILILEGGYNLASISESMAACTHSLLGDPPPQLTLLRPPQSGALVSISEVIQVHRKYWRSLRLMKMEDKEECSSSRLVIKKLPPTASPVSAKEMTTPKGKVPEESVRKTIAALPGKESTLGQAKSKMAKAVLAQGQSSEQAAKGTTLDLATSKETVGGATTDLWASAAAPENFPNQTTSVEALGETEPTPPASHTNKQTTGASPLQGVTAQQSLQLGVLSTLELSREAEEAHDSEEGLLGEAAGGQDMNSLMLTQGFGDFNTQDVFYAVTPLSWCPHLMAVCPIPAAGLDVSQPCKTCGTVQENWVCLTCYQVYCSRYVNAHMVCHHEASEHPLVLSCVDLSTWCYVCQAYVHHEDLQDVKNAAHQNKFGEDMPHSH

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites