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Lactase/phlorizin hydrolase

Summary

UniProt ID

W5PLZ6

Gene Symbol

LCT
LPH

Organism

Ovis aries (sheep)

External Links

Annotation

Keyword

Cell membrane
Glycoprotein
Glycosidase
Multifunctional enzyme
Reference proteome
Signal
Transmembrane helix
Zymogen

Gene Ontology (GO)

Displaying **all 4** entries
GO Term
lactose catabolic process
glycosylceramide catabolic process
cellobiose catabolic process
quercetin catabolic process

Displaying **all 2** entries
GO Term
apical plasma membrane
cytosol

Displaying **all 5** entries
GO Term
phlorizin hydrolase activity
galactosylceramidase activity
glucosylceramidase activity
lactase activity
beta-glucosidase activity

Annotation information from UniProt.

Sequence

MELAWHLVLIVLLSFSCWGLDWDSDKNFISAAGPLTNNLLHNLRDPLGNQDPPFVAEDEEIYVCRQPLPAFLPEYFRSVRASMITHYKVFLPWAQLLPEGISENPDKGTVLCYRQLLEALKTAQLQPLVVLHHQTLPASTLQRTEAFADLFAAYASFAFRSFGDLVEIWFTFSDLERVITKLPHQESRSSRLQILTDAHRKAYEIYQEKYAAQGGKLSVVLQAEMVSKLLLEPSTSVLVKDAVDFVSLDLSYECHNEADLPQKLSELQTIEPKVKVFIFSLKLQNCLSTGNDIAQLLFGLLKAINEDQVLVVGFDISTFLSCPSSSKKSWACSLSDSLTLQTALQLGPDTAAYAWPPCSAYQRVWEAFANQSKAERDAFLQDVFPEGFLWGVSTGAFNVEGGWAEDGRGPSIWDRVGHQNTIKGQATPEVASDSYHKVDTDVALLRGLQAQVYKFSISWSRIFPTGQGHNPNPRGVAYYNKLIDSLLDSHIEPMATLFHWDLPQALQDRGGWQSEDVVDAFLDYAAFCFSTFGDRVKLWVTFHEPWVMSYAGYGTGQHAPGISDPGVASFKKVAHMVLKAHAKAWHLYNSHHRPQQQGRVGIVLNSDWAEPLSPERPEDLRAAERFLHFMLGWFAHPIFVDGDYPAALRAQIQQMNKQCPSPVAQLPEFTEAEKQLLKGSADFLGLSHYTSRLVSTAQGDTCIPSYDTIGGFSQHIDPMWPQTASSWIRVVPWGIRRLLKFVSLEYTKGKVPIYLAGNGMPIGESEDLIDDSLRVDYFNQYINEVLKAIKEDSVAVQSYVARSFIDGFEGPSGYSQRFGLYHVNFNDSSRPRTARKSAYFFTSMIEKNGFLNKVVKRQSSPGIANIPRKIRAFTFPSEVPSKAKVVWEKFSNQPKFERDLFYHGTFRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDVACDSYNHLDADLNMLQALKVKAYRFSISWSRIFPTGRNTSVNTHGVDYYNKLINGLVENNISPMVTLFHWDLPQALQDIGGWENPSLIDLFNSYADFCFQTFGDRVKFWMTFNEPTYQAWLGYGSGEFPPNVNDPGWGPYRIGHTIIKAHARVYHTYDEKYRQEQKGVISLSLSSHWAEPQSLVPRDVEAADRMLQFSLGWFAHPIFRNGDYPDAMKWKVGNRSELQHLATSRLPSFTEEEKRYIAATADVFCLNTYSSRIVQHTTPRLNPPSYTSDQELLEWEDTSWPATAMNRAAAWGTRRLLNWIKEEYGDIPVYITENGVGLTDPELEDTDRIFYHKTYINEALKAYRLDGVNLRGYAAWSLMDNFEWLNGYTVKFGLYHVDFNDVNRSRTARASARYYTEVITNNGMPLSKEDEFLYGQFPKDFIWSAATAAYQIEGAWRADGKGLSIWDTFSHTPLKVENNDTGDVACDSYHKIAEDLVALQTLGVTHYRLSISWTRILPDGTNKYVNEAGLNYYVRLIDTLLAANIQPQVTIYHWDLPQALQDVGGWENETIVQRFKEYAEVLFQRLGDKVKFWITLNEPYVVANQGYGYGTAAPGISFRPGTAPYIVGHNLIKAHAEVWHLYNDVYRARQGGIISITISSDWAEPRDPSNQEDVEAARRYVQFMGGWFAHPIFKNGDYPEVMKTRIRDRSLAEGLNKSRLPEFTESEKRRINGTYDFFGFNHYTTVLAYNLNYASWISSFDADRGVASITDRSWPDSGSFWLKMTPFGFRRILNWLKEEYNNPPIYVTENGVSHRGEANLNDTSRIYYLRSYINEALKALQDKVDLRGYTVWTLMDNFEWATGFSDKFGLHFVNYTDPALPRIPRESAKVYASIIRCRGFPDPAAGPHACLQQEDAEPTASPASPVSQKIQFLGLRLSTTEAQTALNVLFAFMLLGVCGVAFLSYKYFKHSKQKHTQPGEHELSHRSSF

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying entries **1 - 10** of 15 in total

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Position	Description	Source
370	N-linked (GlcNAc...) asparagine	UniProt
826	N-linked (GlcNAc...) asparagine	UniProt
937	N-linked (GlcNAc...) asparagine	UniProt
949	N-linked (GlcNAc...) asparagine	UniProt
992	N-linked (GlcNAc...) asparagine	UniProt
1014	N-linked (GlcNAc...) asparagine	UniProt
1038	N-linked (GlcNAc...) asparagine	UniProt
1176	N-linked (GlcNAc...) asparagine	UniProt
1345	N-linked (GlcNAc...) asparagine	UniProt
1421	N-linked (GlcNAc...) asparagine	UniProt