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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Complement C2
Summary
- UniProt ID
- P06681
- Gene Symbol
-
- C2
- Organism
- Homo sapiens (human)
External Links
- GlycoProtDB
- GPDB0011405
- GlyConnect
- GlyGen
- P06681
- PubChem
- P06681
Annotation
- Keyword
-
- 3D-structure
- Age-related macular degeneration
- Alternative splicing
- Complement pathway
- Direct protein sequencing
- Disease variant
- Disulfide bond
- Glycoprotein
- Metal-binding
- Reference proteome
- Repeat
- Secreted
- Serine protease
- Signal
- Sushi
- Gene Ontology (GO)
| GO Term |
|---|
| extracellular region |
| extracellular space |
| classical-complement-pathway C3/C5 convertase complex |
| extracellular exosome |
| GO Term |
|---|
| metal ion binding |
| serine-type endopeptidase activity |
Sequence
MGPLMVLFCLLFLYPGLADSAPSCPQNVNISGGTFTLSHGWAPGSLLTYSCPQGLYPSPASRLCKSSGQWQTPGATRSLSKAVCKPVRCPAPVSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWDGETAVCDNGAGHCPNPGISLGAVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNGVWSGTEPICRQPYSYDFPEDVAPALGTSFSHMLGATNPTQKTKESLGRKIQIQRSGHLNLYLLLDCSQSVSENDFLIFKESASLMVDRIFSFEINVSVAIITFASEPKVLMSVLNDNSRDMTEVISSLENANYKDHENGTGTNTYAALNSVYLMMNNQMRLLGMETMAWQEIRHAIILLTDGKSNMGGSPKTAVDHIREILNINQKRNDYLDIYAIGVGKLDVDWRELNELGSKKDGERHAFILQDTKALHQVFEHMLDVSKLTDTICGVGNMSANASDQERTPWHVTIKPKSQETCRGALISDQWVLTAAHCFRDGNDHSLWRVNVGDPKSQWGKEFLIEKAVISPGFDVFAKKNQGILEFYGDDIALLKLAQKVKMSTHARPICLPCTMEANLALRRPQGSTCRDHENELLNKQSVPAHFVALNGSKLNINLKMGVEWTSCAEVVSQEKTMFPNLTDVREVVTDQFLCSGTQEDESPCKGESGGAVFLERRFRFFQVGLVSWGLYNPCLGSADKNSRKRAPRSKVPPPRDFHINLFRMQPWLRQHLGDVLNFLPL
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Activation of C3 and C5 | Homo sapiens |
| Initial triggering of complement | Homo sapiens |
| Regulation of Complement cascade | Homo sapiens |
