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Insulin-like growth factor-binding protein 3

Summary

UniProt ID

P47878

Gene Symbol

Igfbp3
Igfbp-3

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB: GPDB0003635
PubChem: P47878

Annotation

Keyword

Apoptosis
Disulfide bond
Glycoprotein
Growth factor binding
Phosphoprotein
Reference proteome
Secreted
Signal

Gene Ontology (GO)

Displaying entries **1 - 10** of 19 in total

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GO Term
regulation of cell growth
osteoblast differentiation
negative regulation of protein phosphorylation
MAPK cascade
apoptotic process
negative regulation of cell population proliferation
regulation of glucose metabolic process
regulation of growth
positive regulation of cardiac muscle cell apoptotic process
negative regulation of smooth muscle cell migration

Displaying **all 6** entries
GO Term
heterochromatin
extracellular space
nucleus
platelet alpha granule
insulin-like growth factor ternary complex
insulin-like growth factor binary complex

Displaying **all 5** entries
GO Term
insulin-like growth factor I binding
insulin-like growth factor II binding
fibronectin binding
insulin-like growth factor binding
protein tyrosine phosphatase activator activity

Annotation information from UniProt.

Sequence

MHPARPALWAAALTALTLLRGPPVARAGAGAVGAGPVVRCEPCDARALSQCAPPPTAPACTELVREPGCGCCLTCALREGDACGVYTERCGTGLRCQPRPAEQYPLRALLNGRGFCANASAAGSLSTYLPSQPAPGNISESEEEHNAGSVESQVVPSTHRVTDSKFHPLHAKMDVIKKGHARDSQRYKVDYESQSTDTQNFSSESKRETEYGPCRREMEDTLNHLKFLNVLSPRGVHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPGYDTKGKDDVHCLSVQSQ

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 3** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
118		23002422
137		23002422
200

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 3** entries
Pathway Name	Organism
Post-translational protein phosphorylation	Mus musculus
Regulation of IGF Activity by IGFBP	Mus musculus
TP53 Regulates Transcription of Death Receptors and Ligands	Mus musculus