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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Phosphatidylcholine-sterol acyltransferase
Summary
- UniProt ID
- P04180
- Gene Symbol
-
- LCAT
- Organism
- Homo sapiens (human)
External Links
- GlycoProtDB
- GPDB0011357
- GlyConnect
- GlyGen
- P04180
- PubChem
- P04180
- SwissLipids
- The Human Metabolome Database
- HMDBP00069
Annotation
- Keyword
-
- 3D-structure
- Acyltransferase
- Cholesterol metabolism
- Corneal dystrophy
- Direct protein sequencing
- Disease variant
- Disulfide bond
- Glycoprotein
- Hydrolase
- Reference proteome
- Secreted
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| high-density lipoprotein particle remodeling |
| regulation of high-density lipoprotein particle assembly |
| GO Term |
|---|
| extracellular region |
| extracellular space |
| extracellular exosome |
| high-density lipoprotein particle |
Sequence
MGPPGSPWQWVTLLLGLLLPPAAPFWLLNVLFPPHTTPKAELSNHTRPVILVPGCLGNQLEAKLDKPDVVNWMCYRKTEDFFTIWLDLNMFLPLGVDCWIDNTRVVYNRSSGLVSNAPGVQIRVPGFGKTYSVEYLDSSKLAGYLHTLVQNLVNNGYVRDETVRAAPYDWRLEPGQQEEYYRKLAGLVEEMHAAYGKPVFLIGHSLGCLHLLYFLLRQPQAWKDRFIDGFISLGAPWGGSIKPMLVLASGDNQGIPIMSSIKLKEEQRITTTSPWMFPSRMAWPEDHVFISTPSFNYTGRDFQRFFADLHFEEGWYMWLQSRDLLAGLPAPGVEVYCLYGVGLPTPRTYIYDHGFPYTDPVGVLYEDGDDTVATRSTELCGLWQGRQPQPVHLLPLHGIQHLNMVFSNLTLEHINAILLGAYRQGPPASPTASPEPPPPE
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| HDL remodeling | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0110156 | Charcot-Marie-Tooth disease type 2B1 | |
| DOID:0110157 | Charcot-Marie-Tooth disease type 2J | |
| DOID:0110158 | Charcot-Marie-Tooth disease type 2I | |
| DOID:0110159 | Charcot-Marie-Tooth disease type 2B | |
| DOID:0110160 | Charcot-Marie-Tooth disease axonal type 2T | |
| DOID:0110161 | Charcot-Marie-Tooth disease type 2R | |
| DOID:0110163 | Charcot-Marie-Tooth disease axonal type 2F | |
| DOID:0110164 | Charcot-Marie-Tooth disease type 2D | |
| DOID:0110165 | Charcot-Marie-Tooth disease type 2E | |
| DOID:0110166 | Charcot-Marie-Tooth disease axonal type 2H |
