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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Amyloid-beta precursor protein
Summary
- UniProt ID
- P12023
- Gene Symbol
-
- App
- A4
- AD1
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Amyloid
- Apoptosis
- Cell adhesion
- Cell membrane
- Cell projection
- Coated pit
- Copper
- Cytoplasm
- Cytoplasmic vesicle
- Disulfide bond
- Endocytosis
- Endoplasmic reticulum
- Endosome
- Glycoprotein
- Golgi apparatus
- Heparin-binding
- Iron
- Isopeptide bond
- Metal-binding
- Notch signaling pathway
- Nucleus
- Phosphoprotein
- Reference proteome
- Secreted
- Serine protease inhibitor
- Signal
- Sulfation
- Transmembrane helix
- Ubl conjugation
- Zinc
- Gene Ontology (GO)
| GO Term |
|---|
| amyloid fibril formation |
| cytoplasmic polyadenylation |
| GO Term |
|---|
| apical part of cell |
| dendritic shaft |
| perikaryon |
| membrane raft |
| endoplasmic reticulum |
| extracellular space |
| cytoplasm |
| Golgi apparatus |
| Golgi-associated vesicle |
| plasma membrane |
| GO Term |
|---|
| serine-type endopeptidase inhibitor activity |
| receptor ligand activity |
| RNA polymerase II cis-regulatory region sequence-specific DNA binding |
Sequence
MLPSLALLLLAAWTVRALEVPTDGNAGLLAEPQIAMFCGKLNMHMNVQNGKWESDPSGTKTCIGTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHTHIVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDSVDSADAEEDDSDVWWGGADTDYADGGEDKVVEVAEEEEVADVEEEEADDDEDVEDGDEVEEEAEEPYEEATERTTSTATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCVPFFYGGCGGNRNNFDTEEYCMAVCGSVSTQSLLKTTSEPLPQDPDKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPHHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHPFGVDSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFGHDSGFEVRHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Advanced glycosylation endproduct receptor signaling | Mus musculus |
| Formyl peptide receptors bind formyl peptides and many other ligands | Mus musculus |
| G alpha (i) signalling events | Mus musculus |
| G alpha (q) signalling events | Mus musculus |
| Insertion of tail-anchored proteins into the endoplasmic reticulum membrane | Mus musculus |
| Lysosome Vesicle Biogenesis | Mus musculus |
| Mitochondrial protein degradation | Mus musculus |
| Platelet degranulation | Mus musculus |
| Post-translational protein phosphorylation | Mus musculus |
| Regulation of IGF Activity by IGFBP | Mus musculus |
