Fibroblast growth factor receptor 2

Summary
UniProt ID
P21803
Gene Symbol
  • Fgfr2
  • Bek
  • Ect1
Organism
Mus musculus (house mouse)
External Links
GlycoProtDB
GPDB0003479
GlyGen
P21803
PubChem
P21803
Annotation
Keyword
  • 3D-structure
  • ATP-binding
  • Alternative splicing
  • Apoptosis
  • Cell membrane
  • Cytoplasmic vesicle
  • Disulfide bond
  • Glycoprotein
  • Golgi apparatus
  • Heparin-binding
  • Immunoglobulin domain
  • Phosphoprotein
  • Proto-oncogene
  • Receptor
  • Reference proteome
  • Repeat
  • Signal
  • Transmembrane helix
  • Tyrosine-protein kinase
  • Ubl conjugation
Gene Ontology (GO)
Sequence
MVSWGRFICLVLVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEAYVVAPGESLELQCMLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTAARTVDSETWIFMVNVTDAISSGDDEDDTDSSEDVVSENRSNQRAPYWTNTEKMEKRLHACPAANTVKFRCPAGGNPTSTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCLVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKNGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPVREKEITASPDYLEIAIYCIGVFLIACMVVTVIFCRMKTTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPTNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLTQPLEQYSPSYPDTSSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT
Glycosylation Sites
Displaying all 2 entries
Position Description PubMed ID GlyTouCan ID Source
228
241
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying entries 1 - 10 of 11 in total
Pathway Name Organism
FGFR2b ligand binding and activation Mus musculus
FGFR2c ligand binding and activation Mus musculus
FRS-mediated FGFR2 signaling Mus musculus
Negative regulation of FGFR2 signaling Mus musculus
PI-3K cascade:FGFR2 Mus musculus
PI3K Cascade Mus musculus
PI3K/AKT Signaling Mus musculus
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling Mus musculus
Phospholipase C-mediated cascade; FGFR2 Mus musculus
RAF/MAP kinase cascade Mus musculus

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024