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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Dual specificity mitogen-activated protein kinase kinase 1
Summary
- UniProt ID
- P31938
- Gene Symbol
-
- Map2k1
- Mek1
- Prkmk1
- Organism
- Mus musculus (house mouse)
External Links
- GlycoProtDB
- GPDB0003563
- GlyGen
- P31938
- PubChem
- P31938
- RaftProt
- P31938
Annotation
- Keyword
-
- ATP-binding
- Cytoskeleton
- Direct protein sequencing
- Membrane
- Nucleus
- Phosphoprotein
- Reference proteome
- Serine/threonine-protein kinase
- Tyrosine-protein kinase
- Gene Ontology (GO)
| GO Term |
|---|
| early endosome |
| late endosome |
| endoplasmic reticulum |
| Golgi apparatus |
| cytosol |
| perinuclear region of cytoplasm |
| nucleus |
| mitochondrion |
| plasma membrane |
| cell cortex |
| GO Term |
|---|
| MAP kinase kinase activity |
| MAP-kinase scaffold activity |
| ATP binding |
Sequence
MPKKKPTPIQLNPAPDGSAVNGTSSAETNLEALQKKLEELELDEQQRKRLEAFLTQKQKVGELKDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELLFGCHVEGDAAETPPRPRTPGRPLSSYGMDSRPPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLMVHAFIKRSDAEEVDFAGWLCSTIGLNQPSTPTHAASI
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 21 |
|
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Frs2-mediated activation | Mus musculus |
| MAP2K and MAPK activation | Mus musculus |
| MAPK3 (ERK1) activation | Mus musculus |
| Negative feedback regulation of MAPK pathway | Mus musculus |
| RAF activation | Mus musculus |
| Signal transduction by L1 | Mus musculus |
