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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Palmitoyl-protein thioesterase 1
Summary
- UniProt ID
- P50897
- Gene Symbol
-
- PPT1
- CLN1
- PPT
- Organism
- Homo sapiens (human)
External Links
- GlycoProtDB
- GPDB0011719
- GlyConnect
- GlyGen
- P50897
- PubChem
- P50897
- The Human Metabolome Database
- HMDBP01050
- The O-GlcNAc Database
- P50897
- O-GlcNAcAtlas
- P50897
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Disease variant
- Disulfide bond
- Glycoprotein
- Hydrolase
- Lysosome
- Neuronal ceroid lipofuscinosis
- Reference proteome
- Secreted
- Signal
- Vision
- Gene Ontology (GO)
| GO Term |
|---|
| neurotransmitter secretion |
| nervous system development |
| brain development |
| visual perception |
| protein transport |
| lipid catabolic process |
| protein catabolic process |
| neuron development |
| response to stimulus |
| sphingolipid catabolic process |
| GO Term |
|---|
| cytosol |
| membrane raft |
| synaptic vesicle |
| lysosomal lumen |
| GO Term |
|---|
| long-chain acyl-CoA hydrolase activity |
| palmitoyl-(protein) hydrolase activity |
| lysophosphatidic acid binding |
| sulfatide binding |
Sequence
MASPGCLWLLAVALLPWTCASRALQHLDPPAPLPLVIWHGMGDSCCNPLSMGAIKKMVEKKIPGIYVLSLEIGKTLMEDVENSFFLNVNSQVTTVCQALAKDPKLQQGYNAMGFSQGGQFLRAVAQRCPSPPMINLISVGGQHQGVFGLPRCPGESSHICDFIRKTLNAGAYSKVVQERLVQAEYWHDPIKEDVYRNHSIFLADINQERGINESYKKNLMALKKFVMVKFLNDSIVDPVDSEWFGFYRSGQAKETIPLQETSLYTQDRLGLKEMDNAGQLVFLATEGDHLQLSEEWFYAHIIPFLG
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Fatty acyl-CoA biosynthesis | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:7997 | thyrotoxicosis | |
| DOID:7998 | hyperthyroidism | |
| DOID:863 | nervous system disease | |
| DOID:8866 | actinic keratosis | |
| DOID:8927 | learning disability | |
| DOID:9256 | colorectal cancer | |
| DOID:936 | brain disease | |
| DOID:9505 | cannabis abuse | |
| DOID:9637 | stomatitis | |
| DOID:9673 | ulcerative stomatitis |
