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Receptor tyrosine-protein kinase erbB-2

Summary

UniProt ID

P70424

Gene Symbol

Erbb2
Kiaa3023
Neu

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB: GPDB0003777
PubChem: P70424

Annotation

Keyword

ATP-binding
Activator
Cell membrane
Cell projection
Cytoplasm
Disulfide bond
Endosome
Glycoprotein
Nucleus
Phosphoprotein
Receptor
Reference proteome
Signal
Transcription regulation
Transmembrane helix
Tyrosine-protein kinase

Gene Ontology (GO)

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GO Term
positive regulation of epithelial cell proliferation
glial cell differentiation
Schwann cell development
neurogenesis
positive regulation of cell growth
regulation of microtubule-based process
immature T cell proliferation in thymus
negative regulation of immature T cell proliferation in thymus
intracellular signal transduction
myelination

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GO Term
ERBB3:ERBB2 complex
presynaptic membrane
perinuclear region of cytoplasm
cytoplasm
plasma membrane
microvillus
membrane
cytoplasmic vesicle
neuromuscular junction
myelin sheath

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GO Term
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
protein-containing complex binding
Hsp90 protein binding
ubiquitin protein ligase binding
identical protein binding
ErbB-3 class receptor binding
protein heterodimerization activity
RNA polymerase I core binding
ATP binding

Annotation information from UniProt.

Sequence

MELAAWCRWGFLLALLSPGAAGTQVCTGTDMKLRLPASPETHLDMLRHLYQGCQVVQGNLELTYLPANASLSFLQDIQEVQGYMLIAHNRVKHVPLQRLRIVRGTQLFEDKYALAVLDNRDPLDNVTTAAPGRTPEGLRELQLRSLTEILKGGVLIRGNPQLCYQDMVLWKDVLRKNNQLAPVDMDTNRSRACPPCAPTCKDNHCWGESPEDCQILTGTICTSGCARCKGRLPTDCCHEQCAAGCTGPKHSDCLACLHFNHSGICELHCPALITYNTDTFESMLNPEGRYTFGASCVTTCPYNYLSTEVGSCTLVCPPNNQEVTAEDGTQRCEKCSKPCAGVCYGLGMEHLRGARAITSDNIQEFAGCKKIFGSLAFLPESFDGNPSSGVAPLKPEHLQVFETLEEITGYLYISAWPESFQDLSVFQNLRVIRGRILHDGAYSLTLQGLGIHSLGLRSLRELGSGLALIHRNTHLCFVNTVPWDQLFRNPHQALLHSGNRPEEACGLEGLVCNSLCARGHCWGPGPTQCVNCSQFLRGQECVEECRVWKGLPREYVRGKHCLPCHPECQPQNSSETCYGSEADQCEACAHYKDSSSCVARCPSGVKPDLSYMPIWKYPDEEGICQPCPINCTHSCVDLDERGCPAEQRASPVTFIIATVVGVLLFLIIVVVIGILIKRRRQKIRKYTMRRLLQETELVEPLTPSGAVPNQAQMRILKETELRKLKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSPYVSRLLGICLTSTVQLVTQLMPYGCLLDHVREHRGRLGSQDLLNWCVQIAKGMSYLEEVRLVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFTHQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELVSEFSRMARDPQRFVVIQNEDLGPSSPMDSTFYRSLLEDDDMGELVDAEEYLVPQQGFFSPDPALGTGSTAHRRHRSSSARSGGGELTLGLEPSEEEPPRSPLAPSEGAGSDVFDGDLAVGVTKGLQSLSPHDLSPLQRYSEDPTLPLPPETDGYVAPLACSPQPEYVNQPEVRPQSPLTPEGPPPPIRPAGATLERPKTLSPGKNGVVKDVFAFGGAVENPEYLAPRAGTASQPHPSPAFSPAFDNLYYWDQNSSEQGPPPSTFEGTPTAENPEYLGLDVPV

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 4** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
125		22823882
531		22823882 23002422
572		22823882
630

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

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Pathway Name	Organism
RAF/MAP kinase cascade	Mus musculus
SHC1 events in ERBB2 signaling	Mus musculus
Sema4D induced cell migration and growth-cone collapse	Mus musculus
Signaling by ERBB2	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

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Summary

External Links

Annotation

International Collaboration

Acknowledgements