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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4
Summary
- UniProt ID
- Q11206
- Gene Symbol
-
- ST3GAL4
- CGS23
- NANTA3
- SIAT4C
- STZ
- Organism
- Homo sapiens (human)
External Links
- GlycoProtDB
- GPDB0011826
- GlyGen
- Q11206
- PubChem
- Q11206
- SwissLipids
- The Human Metabolome Database
- HMDBP03118
- The O-GlcNAc Database
- Q11206
- O-GlcNAcAtlas
- Q11206
Annotation
- Keyword
-
- Alternative splicing
- Disulfide bond
- Glycoprotein
- Glycosyltransferase
- Golgi apparatus
- Lipid metabolism
- Reference proteome
- Secreted
- Signal-anchor
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| sialylation |
| oligosaccharide biosynthetic process |
| positive regulation of leukocyte tethering or rolling |
| GO Term |
|---|
| Golgi cisterna membrane |
| Golgi membrane |
| extracellular region |
| membrane |
Sequence
MVSKSRWKLLAMLALVLVVMVWYSISREDRYIELFYFPIPEKKEPCLQGEAESKASKLFGNYSRDQPIFLRLEDYFWVKTPSAYELPYGTKGSEDLLLRVLAITSSSIPKNIQSLRCRRCVVVGNGHRLRNSSLGDAINKYDVVIRLNNAPVAGYEGDVGSKTTMRLFYPESAHFDPKVENNPDTLLVLVAFKAMDFHWIETILSDKKRVRKGFWKQPPLIWDVNPKQIRILNPFFMEIAADKLLSLPMQQPRKIKQKPTTGLLAITLALHLCDLVHIAGFGYPDAYNKKQTIHYYEQITLKSMAGSGHNVSQEALAIKRMLEMGAIKNLTSF
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Keratan sulfate biosynthesis | Homo sapiens |
| Lewis blood group biosynthesis | Homo sapiens |
| Maturation of protein 3a | Homo sapiens |
| Maturation of protein 3a | Homo sapiens |
| Maturation of spike protein | Homo sapiens |
| N-Glycan antennae elongation | Homo sapiens |
| Pre-NOTCH Processing in Golgi | Homo sapiens |
| Sialic acid metabolism | Homo sapiens |
| Termination of O-glycan biosynthesis | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0110754 | type 1 diabetes mellitus 17 | |
| DOID:0110755 | type 1 diabetes mellitus 18 | |
| DOID:0110756 | type 1 diabetes mellitus 19 | |
| DOID:0110757 | type 1 diabetes mellitus 20 | |
| DOID:0110758 | type 1 diabetes mellitus 21 | |
| DOID:0110759 | type 1 diabetes mellitus 22 | |
| DOID:0110760 | type 1 diabetes mellitus 23 | |
| DOID:0110761 | type 1 diabetes mellitus 24 | |
| DOID:0111192 | facioscapulohumeral muscular dystrophy 1 | |
| DOID:0111391 | mucopolysaccharidosis IVA |
