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ALK tyrosine kinase receptor

Summary

UniProt ID

F8W3R9

Gene Symbol

Organism

Danio rerio (zebrafish)

External Links

Annotation

Keyword

ATP-binding
Cell membrane
Disulfide bond
Glycoprotein
Receptor
Reference proteome
Signal
Transmembrane helix
Tyrosine-protein kinase

Gene Ontology (GO)

Displaying **all 6** entries
GO Term
positive regulation of MAPK cascade
transmembrane receptor protein tyrosine kinase signaling pathway
phosphorylation
regulation of cell population proliferation
positive regulation of neurogenesis
regulation of neuron differentiation

Displaying **all 2** entries
GO Term
plasma membrane
receptor complex

Displaying **all 2** entries
GO Term
ATP binding
transmembrane receptor protein tyrosine kinase activity

Annotation information from UniProt.

Sequence

MIARILYFFLWSAAFLPELQCASQRTADALTTFPTSAFINGTDRKDSNQTSTSRIKRKTLSVDFAVPSLLRYYLALFIKRPLNGDCLSFNGCYTVRANLLMRCVPLQKTIAGLLDAKLAAMNVNRSSTGQLPYRQKRPVPKVLNLGLTSASRKSNQVVVEVGEEMVKTGCGGLHVYEDAPVVFLEMDLTRILEWWLGAEGGRLRVRLMPERKVQVPGKEDKYSAAIRASDARLFIQIASSERPSSTISRNPTVAPKYWNFSWIAEDELTFPEDPVSTSDCTSKAKSCDRRPDGYYPEFAWSLTSAEDSWAIDQTMVKTKASSQGWEEGRFLTVNSSALTGPWVLSPWFRAAHRPCGLDITVFLHPRQSGRYTVWLIERDKPPLALLTTEHPHVIGWAVVHLSLAARSKPFRISSSYSQPGEIETATYDPRYSTNCTTRSSQNVTLRGRYHCRGGREINVSQLCDFSIDCPQGDDEGEHCRQFLNGSYCSFGREDCGWQPVQGRGPQWRAHPSIPQSLRSSCPSPGALLAIDSQPKGQRGSAQVRSPLFFYPLRNAPCMVKFWVCGSSNGALSLWITENSTGPEGQRSLWNSTSEANMGKGWKLITLPLFGLVDLFYLQFSADISSSSGIAFAVDNFTLSMECFLETNGEFPPVAPISPTQALFTQSNENIKTTTTLYGGPGASTESVKWIFHTCGATGQDGPTPTQCSNSYRNTNVNVTVGTKGPFKGIQMWQVPETRKYRITAYGAAGGRSVLAVHKSHGVYMTGDFLLQKDELLYILVGQEGEDACPNMVPTMDRICREQQGPSINKTQLKGGGGGGGGGTYVFKVVNGVHIPLLIAAGGGGRGYSSQSETPEEVMDRDPSIPGRNGKSGTAGGGGGWNDSAPVPQGGRPLILGGQGGEPCQAMGWKTRGGFGGGGGACTAGGGGGGYRGGSAWHDNDPRKDGDDGTSYISPDGEMYLEPLKGMEGNGEVIINPVQNCSHCESGDCHETSEGMVCYCDEELTLAPDGVSCINSTELPLLPAQPSLSHLALGLSVGTSALIAALLLAVSGVMIMYRRKHTELQSIQLELQSPDCKLSKLRASTIMTDYNPNYCFGGKTASVNDLKEVPRRNISLTRGLGHGAFGEVYEGLAVGIPGEPSPMQVAVKTLPEVCSEQDELDFLMEALIISKFSHQNIVRCIGVSLQALPHFILLELMAGGDLKSFLRETRPRLEHPSSLTMVDLLNIARDIARGCQYLEENQFIHRDIAARNCLLTCKGPGRVAKIGDFGMARDIYRASYYRKGGRAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSRSNQEVLEFVTNGGRMDPPKNCPGPVYRIMTQSWQHQPEDRPNFSTILERIDYCLQDPDVVNVPLPVEYGPIPEEEERVPMRPEDPSAPSLLVSPQGTEDVPSATHSAQSKKDGEAIHMANLSTDSKLPPVPPSQPHPHHHLQTPVVTAPVPASKPSSTTSNAQDGGHVNLGFMQAHSSEKESRNRKPTNLWNPTYGSWFLQQQQKRQQVQAQRQTSGPRIPGEGQEQVGRTVTVAEALGLQQQHKQQQYQQQLQRQQQQQQQQQQQQGLCRPLLPPPPPPAPTPLLLDSATLAPVPLYRLRRFPCGNIGYGYQEQGLPMEPMQGPQLPPPHPGQQRPISLTRASGPEDSRPLLVTMGTVQDSRLPKMEGHNATVL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying entries **1 - 10** of 17 in total

1

2

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Position	Description	Source
40	N-linked (GlcNAc...) asparagine	UniProt
48	N-linked (GlcNAc...) asparagine	UniProt
124	N-linked (GlcNAc...) asparagine	UniProt
259	N-linked (GlcNAc...) asparagine	UniProt
334	N-linked (GlcNAc...) asparagine	UniProt
434	N-linked (GlcNAc...) asparagine	UniProt
442	N-linked (GlcNAc...) asparagine	UniProt
458	N-linked (GlcNAc...) asparagine	UniProt
484	N-linked (GlcNAc...) asparagine	UniProt
578	N-linked (GlcNAc...) asparagine	UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 2** entries
Pathway Name	Organism
MDK and PTN in ALK signaling	Danio rerio
Signaling by ALK	Danio rerio

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

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International Collaboration

Acknowledgements