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Angiotensin-converting enzyme

Summary

UniProt ID

P09470

Gene Symbol

Ace
Dcp1

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB

GPDB0003321

GlyConnect

2129

GlyGen

P09470

PubChem

P09470

The O-GlcNAc Database

P09470

RaftProt

P09470

Annotation

Keyword

Alternative promoter usage
Calmodulin-binding
Carboxypeptidase
Cell membrane
Cytoplasm
Direct protein sequencing
Disulfide bond
Glycoprotein
Metal-binding
Metalloprotease
Phosphoprotein
Reference proteome
Repeat
Secreted
Signal
Transmembrane helix
Zinc

Gene Ontology (GO)

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GO Term
kidney development
neutrophil mediated immunity
regulation of systemic arterial blood pressure by renin-angiotensin
peptide metabolic process
spermatogenesis
female pregnancy
regulation of blood pressure
male gonad development
embryo development ending in birth or egg hatching
post-transcriptional regulation of gene expression

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GO Term
extracellular space
cytoplasm
lysosome
plasma membrane
vesicle
extracellular exosome
brush border membrane
endosome
external side of plasma membrane
basal plasma membrane

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GO Term
peptidase activity
heterocyclic compound binding
chloride ion binding
mitogen-activated protein kinase kinase binding
bradykinin receptor binding
tripeptidyl-peptidase activity
carboxypeptidase activity
metalloendopeptidase activity
metallopeptidase activity
calmodulin binding

Annotation information from UniProt.

Sequence

MGAASGQRGRWPLSPPLLMLSLLVLLLQPSPAPALDPGLQPGNFSPDEAGAQLFAESYNSSAEVVMFQSTVASWAHDTNITEENARRQEEAALVSQEFAEVWGKKAKELYESIWQNFTDSKLRRIIGSIRTLGPANLPLAQRQQYNSLLSNMSRIYSTGKVCFPNKTATCWSLDPELTNILASSRSYAKLLFAWEGWHDAVGIPLKPLYQDFTAISNEAYRQDDFSDTGAFWRSWYESPSFEESLEHIYHQLEPLYLNLHAYVRRALHRRYGDKYVNLRGPIPAHLLGDMWAQSWENIYDMVVPFPDKPNLDVTSTMVQKGWNATHMFRVSEEFFTSLGLSPMPPEFWAESMLEKPTDGREVVCHASAWDFYNRKDFRIKQCTRVTMEQLATVHHEMGHVQYYLQYKDLHVSLRRGANPGFHEAIGDVLALSVSTPAHLHKIGLLDHVTNDIESDINYLLKMALEKIAFLPFGYLVDQWRWGVFSGRTPPSRYNFDWWYLRTKYQGICPPVARNETHFDAGAKFHIPNVTPYIRYFVSFVLQFQFHQALCKEAGHQGPLHQCDIYQSAQAGAKLKQVLQAGCSRPWQEVLKDLVGSDALDAKALLEYFQPVSQWLEEQNQRNGEVLGWPENQWRPPLPDNYPEGIDLETDEAKADRFVEEYDRTAQVLLNEYAEANWQYNTNITIEGSKILLEKSTEVSNHTLKYGTRAKTFDVSNFQNSSIKRIIKKLQNLDRAVLPPKELEEYNQILLDMETTYSLSNICYTNGTCMPLEPDLTNMMATSRKYEELLWAWKSWRDKVGRAILPFFPKYVEFSNKIAKLNGYTDAGDSWRSLYESDNLEQDLEKLYQELQPLYLNLHAYVRRSLHRHYGSEYINLDGPIPAHLLGNMWAQTWSNIYDLVAPFPSAPNIDATEAMIKQGWTPRRIFKEADNFFTSLGLLPVPPEFWNKSMLEKPTDGREVVCHPSAWDFYNGKDFRIKQCTSVNMEDLVIAHHEMGHIQYFMQYKDLPVTFREGANPGFHEAIGDIMALSVSTPKHLYSLNLLSTEGSGYEYDINFLMKMALDKIAFIPFSYLIDQWRWRVFDGSITKENYNQEWWSLRLKYQGLCPPVPRSQGDFDPGSKFHVPANVPYVRYFVSFIIQFQFHEALCRAAGHTGPLHKCDIYQSKEAGKLLADAMKLGYSKPWPEAMKLITGQPNMSASAMMNYFKPLTEWLVTENRRHGETLGWPEYNWAPNTARAEGSTAESNRVNFLGLYLEPQQARVGQWVLLFLGVALLVATVGLAHRLYNIRNHHSLRRPHRGPQFGSEVELRHS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

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Position	Description	PubMed ID	GlyTouCan ID	Source
59	N-linked (GlcNAc...) asparagine			UniProt GlyGen
79	N-linked (GlcNAc...) asparagine			UniProt GlyGen
116	N-linked (GlcNAc...) asparagine			GlycoProtDB UniProt GlyGen
151	N-linked (GlcNAc...) asparagine	16944957	G25079LO	GlycoProtDB UniProt GlyGen
165	N-linked (GlcNAc...) asparagine		G72735IY G57776ZU	GlycoProtDB UniProt GlyGen GlyConnect
323	N-linked (GlcNAc...) asparagine		G87389XI	GlycoProtDB UniProt GlyGen
514	N-linked (GlcNAc...) asparagine		G64527OM G72735IY G18647XP G82119TF G05724UK G39188ZX G06110VR	GlycoProtDB UniProt GlyGen GlyConnect
528			G72735IY	GlyGen GlyConnect
682	N-linked (GlcNAc...) asparagine			UniProt GlyGen
700	N-linked (GlcNAc...) (complex) asparagine		G23863VK G25637MV G50282JC G74724QE	GlycoProtDB UniProt GlyGen GlyConnect