GlyCosmos Portal

GlyCOVID

GlyCOVID is a dataset of RDFized COVID-19 data related to glycans. Resources will be added incrementally as publications are curated.

Longitudinal Development of Antibody Responses in COVID-19 Patients of Different Severity with ELISA, Peptide, and Glycan Arrays: An Immunological Case Series.
Heidepriem J, et al.
Pathogens. 2021; 10(4):438. https://doi.org/10.3390/pathogens10040438

A longitudinal analysis of three COVID-19 patients with moderate (#1) and mild disease (#2 and #3) was published. Antibody serum responses were analyzed using spike glycoprotein enzyme linked immunosorbent assay (ELISA), full-proteome peptide, and glycan microarrays. In this Glycovid dataset, the data from these glycan microarray experiments have been RDFized. Fluorescence intensity is given in arbitrary fluorescence units (AFU) as reported in this publication.

Source	Last Updated
PSICQUIC	March 30, 2022

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Antibody	Patient	Onset (days)	Symptom	GlyTouCan ID ▲	Arbitrary Fluorescence Units (AFU)
IgA	Patient 2	3	mild	G00066MO	1275
IgG	Patient 2	3	mild	G00066MO	251
IgM	Patient 2	3	mild	G00066MO	2949
IgA	Patient 3	-180	mild	G00066MO	319
IgA	Patient 3	11	mild	G00066MO	426
IgG	Patient 3	-180	mild	G00066MO	81
IgG	Patient 3	11	mild	G00066MO	190
IgM	Patient 3	-180	mild	G00066MO	235
IgA	Patient 3	4	mild	G00066MO	527
IgG	Patient 3	4	mild	G00066MO	212
IgM	Patient 3	11	mild	G00066MO	453
IgM	Patient 3	4	mild	G00066MO	551
IgA	Patient 4	12	mild	G00066MO	460
IgG	Patient 4	12	mild	G00066MO	120
IgM	Patient 4	12	mild	G00066MO	238
IgA	Patient 1	10	moderate	G00068MO	316
IgA	Patient 1	22	moderate	G00068MO	289
IgA	Patient 1	6	moderate	G00068MO	305
IgG	Patient 1	10	moderate	G00068MO	19
IgG	Patient 1	22	moderate	G00068MO	22
IgG	Patient 1	6	moderate	G00068MO	24
IgM	Patient 1	10	moderate	G00068MO	27
IgM	Patient 1	22	moderate	G00068MO	30
IgM	Patient 1	6	moderate	G00068MO	26
IgA	Patient 2	15	mild	G00068MO	248