GlyCosmos Portal

GlyCOVID

GlyCOVID is a dataset of RDFized COVID-19 data related to glycans. Resources will be added incrementally as publications are curated.

Longitudinal Development of Antibody Responses in COVID-19 Patients of Different Severity with ELISA, Peptide, and Glycan Arrays: An Immunological Case Series.
Heidepriem J, et al.
Pathogens. 2021; 10(4):438. https://doi.org/10.3390/pathogens10040438

A longitudinal analysis of three COVID-19 patients with moderate (#1) and mild disease (#2 and #3) was published. Antibody serum responses were analyzed using spike glycoprotein enzyme linked immunosorbent assay (ELISA), full-proteome peptide, and glycan microarrays. In this Glycovid dataset, the data from these glycan microarray experiments have been RDFized. Fluorescence intensity is given in arbitrary fluorescence units (AFU) as reported in this publication.

Source	Last Updated
PSICQUIC	March 30, 2022

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Antibody	Patient	Onset (days)	Symptom	GlyTouCan ID ▲	Arbitrary Fluorescence Units (AFU)
IgA	Patient 1	10	moderate	G64669AQ	325
IgA	Patient 1	22	moderate	G64669AQ	301
IgA	Patient 1	6	moderate	G64669AQ	301
IgG	Patient 1	10	moderate	G64669AQ	23
IgG	Patient 1	22	moderate	G64669AQ	24
IgM	Patient 1	10	moderate	G64669AQ	30
IgM	Patient 1	22	moderate	G64669AQ	49
IgG	Patient 1	6	moderate	G64669AQ	24
IgM	Patient 1	6	moderate	G64669AQ	31
IgA	Patient 2	15	mild	G64669AQ	302
IgA	Patient 2	24	mild	G64669AQ	346
IgG	Patient 2	15	mild	G64669AQ	3026
IgG	Patient 2	24	mild	G64669AQ	2955
IgM	Patient 2	15	mild	G64669AQ	104
IgM	Patient 2	24	mild	G64669AQ	106
IgA	Patient 2	3	mild	G64669AQ	340
IgG	Patient 2	3	mild	G64669AQ	3726
IgM	Patient 2	3	mild	G64669AQ	111
IgA	Patient 3	-180	mild	G64669AQ	617
IgA	Patient 3	11	mild	G64669AQ	1265
IgG	Patient 3	-180	mild	G64669AQ	2537
IgM	Patient 3	-180	mild	G64669AQ	1075
IgA	Patient 3	4	mild	G64669AQ	847
IgG	Patient 3	11	mild	G64669AQ	3049
IgG	Patient 3	4	mild	G64669AQ	2347