GlyCosmos Portal

GlyCOVID

GlyCOVID is a dataset of RDFized COVID-19 data related to glycans. Resources will be added incrementally as publications are curated.

Longitudinal Development of Antibody Responses in COVID-19 Patients of Different Severity with ELISA, Peptide, and Glycan Arrays: An Immunological Case Series.
Heidepriem J, et al.
Pathogens. 2021; 10(4):438. https://doi.org/10.3390/pathogens10040438

A longitudinal analysis of three COVID-19 patients with moderate (#1) and mild disease (#2 and #3) was published. Antibody serum responses were analyzed using spike glycoprotein enzyme linked immunosorbent assay (ELISA), full-proteome peptide, and glycan microarrays. In this Glycovid dataset, the data from these glycan microarray experiments have been RDFized. Fluorescence intensity is given in arbitrary fluorescence units (AFU) as reported in this publication.

Source	Last Updated
PSICQUIC	March 30, 2022

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Antibody	Patient	Onset (days)	Symptom	GlyTouCan ID ▲	Arbitrary Fluorescence Units (AFU)
IgM	Patient 3	11	mild	G64669AQ	3180
IgM	Patient 3	4	mild	G64669AQ	1821
IgA	Patient 4	12	mild	G64669AQ	348
IgG	Patient 4	12	mild	G64669AQ	158
IgM	Patient 4	12	mild	G64669AQ	168
IgA	Patient 1	10	moderate	G65889KE	433
IgA	Patient 1	22	moderate	G65889KE	420
IgA	Patient 1	6	moderate	G65889KE	380
IgG	Patient 1	10	moderate	G65889KE	46
IgG	Patient 1	22	moderate	G65889KE	45
IgM	Patient 1	10	moderate	G65889KE	60
IgM	Patient 1	22	moderate	G65889KE	62
IgG	Patient 1	6	moderate	G65889KE	38
IgM	Patient 1	6	moderate	G65889KE	37
IgA	Patient 2	15	mild	G65889KE	291
IgA	Patient 2	24	mild	G65889KE	332
IgG	Patient 2	15	mild	G65889KE	70
IgG	Patient 2	24	mild	G65889KE	82
IgM	Patient 2	15	mild	G65889KE	95
IgM	Patient 2	24	mild	G65889KE	107
IgA	Patient 2	3	mild	G65889KE	320
IgG	Patient 2	3	mild	G65889KE	87
IgM	Patient 2	3	mild	G65889KE	143
IgA	Patient 3	-180	mild	G65889KE	284
IgA	Patient 3	11	mild	G65889KE	377