GlyCosmos Portal

GlyCOVID

GlyCOVID is a dataset of RDFized COVID-19 data related to glycans. Resources will be added incrementally as publications are curated.

Longitudinal Development of Antibody Responses in COVID-19 Patients of Different Severity with ELISA, Peptide, and Glycan Arrays: An Immunological Case Series.
Heidepriem J, et al.
Pathogens. 2021; 10(4):438. https://doi.org/10.3390/pathogens10040438

A longitudinal analysis of three COVID-19 patients with moderate (#1) and mild disease (#2 and #3) was published. Antibody serum responses were analyzed using spike glycoprotein enzyme linked immunosorbent assay (ELISA), full-proteome peptide, and glycan microarrays. In this Glycovid dataset, the data from these glycan microarray experiments have been RDFized. Fluorescence intensity is given in arbitrary fluorescence units (AFU) as reported in this publication.

Source	Last Updated
PSICQUIC	March 30, 2022

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Antibody	Patient	Onset (days)	Symptom	GlyTouCan ID ▲	Arbitrary Fluorescence Units (AFU)
IgA	Patient 2	3	mild	G66937TJ	500
IgG	Patient 2	3	mild	G66937TJ	57
IgM	Patient 2	3	mild	G66937TJ	334
IgA	Patient 3	-180	mild	G66937TJ	293
IgA	Patient 3	11	mild	G66937TJ	426
IgG	Patient 3	-180	mild	G66937TJ	48
IgM	Patient 3	-180	mild	G66937TJ	134
IgA	Patient 3	4	mild	G66937TJ	456
IgG	Patient 3	11	mild	G66937TJ	57
IgG	Patient 3	4	mild	G66937TJ	50
IgM	Patient 3	11	mild	G66937TJ	246
IgM	Patient 3	4	mild	G66937TJ	218
IgA	Patient 4	12	mild	G66937TJ	396
IgG	Patient 4	12	mild	G66937TJ	85
IgM	Patient 4	12	mild	G66937TJ	252
IgA	Patient 1	10	moderate	G67045LB	420
IgA	Patient 1	22	moderate	G67045LB	386
IgA	Patient 1	6	moderate	G67045LB	389
IgG	Patient 1	10	moderate	G67045LB	27
IgG	Patient 1	22	moderate	G67045LB	34
IgM	Patient 1	10	moderate	G67045LB	65
IgM	Patient 1	22	moderate	G67045LB	181
IgG	Patient 1	6	moderate	G67045LB	29
IgM	Patient 1	6	moderate	G67045LB	75
IgA	Patient 2	15	mild	G67045LB	341