GlyCosmos Portal

GlyCOVID

GlyCOVID is a dataset of RDFized COVID-19 data related to glycans. Resources will be added incrementally as publications are curated.

Longitudinal Development of Antibody Responses in COVID-19 Patients of Different Severity with ELISA, Peptide, and Glycan Arrays: An Immunological Case Series.
Heidepriem J, et al.
Pathogens. 2021; 10(4):438. https://doi.org/10.3390/pathogens10040438

A longitudinal analysis of three COVID-19 patients with moderate (#1) and mild disease (#2 and #3) was published. Antibody serum responses were analyzed using spike glycoprotein enzyme linked immunosorbent assay (ELISA), full-proteome peptide, and glycan microarrays. In this Glycovid dataset, the data from these glycan microarray experiments have been RDFized. Fluorescence intensity is given in arbitrary fluorescence units (AFU) as reported in this publication.

Source	Last Updated
PSICQUIC	March 30, 2022

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Antibody	Patient	Onset (days)	Symptom	GlyTouCan ID ▲	Arbitrary Fluorescence Units (AFU)
IgM	Patient 3	11	mild	G68703KI	8187
IgM	Patient 3	4	mild	G68703KI	8163
IgA	Patient 4	12	mild	G68703KI	447
IgG	Patient 4	12	mild	G68703KI	139
IgM	Patient 4	12	mild	G68703KI	301
IgA	Patient 1	10	moderate	G69912LP	361
IgA	Patient 1	22	moderate	G69912LP	340
IgA	Patient 1	6	moderate	G69912LP	282
IgG	Patient 1	10	moderate	G69912LP	23
IgG	Patient 1	22	moderate	G69912LP	25
IgM	Patient 1	10	moderate	G69912LP	35
IgM	Patient 1	22	moderate	G69912LP	78
IgG	Patient 1	6	moderate	G69912LP	23
IgM	Patient 1	6	moderate	G69912LP	33
IgA	Patient 2	15	mild	G69912LP	664
IgA	Patient 2	24	mild	G69912LP	737
IgG	Patient 2	15	mild	G69912LP	19530
IgG	Patient 2	24	mild	G69912LP	20639
IgM	Patient 2	15	mild	G69912LP	394
IgM	Patient 2	24	mild	G69912LP	443
IgA	Patient 2	3	mild	G69912LP	788
IgG	Patient 2	3	mild	G69912LP	25678
IgM	Patient 2	3	mild	G69912LP	570
IgA	Patient 3	-180	mild	G69912LP	3400
IgA	Patient 3	11	mild	G69912LP	3319