GlyCosmos Portal

GlyCOVID

GlyCOVID is a dataset of RDFized COVID-19 data related to glycans. Resources will be added incrementally as publications are curated.

Longitudinal Development of Antibody Responses in COVID-19 Patients of Different Severity with ELISA, Peptide, and Glycan Arrays: An Immunological Case Series.
Heidepriem J, et al.
Pathogens. 2021; 10(4):438. https://doi.org/10.3390/pathogens10040438

A longitudinal analysis of three COVID-19 patients with moderate (#1) and mild disease (#2 and #3) was published. Antibody serum responses were analyzed using spike glycoprotein enzyme linked immunosorbent assay (ELISA), full-proteome peptide, and glycan microarrays. In this Glycovid dataset, the data from these glycan microarray experiments have been RDFized. Fluorescence intensity is given in arbitrary fluorescence units (AFU) as reported in this publication.

Source	Last Updated
PSICQUIC	March 30, 2022

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Antibody	Patient	Onset (days)	Symptom	GlyTouCan ID ▲	Arbitrary Fluorescence Units (AFU)
IgA	Patient 2	3	mild	G75896PD	965
IgG	Patient 2	3	mild	G75896PD	165
IgM	Patient 2	3	mild	G75896PD	1443
IgA	Patient 3	-180	mild	G75896PD	313
IgA	Patient 3	11	mild	G75896PD	500
IgG	Patient 3	-180	mild	G75896PD	80
IgM	Patient 3	-180	mild	G75896PD	161
IgA	Patient 3	4	mild	G75896PD	511
IgG	Patient 3	11	mild	G75896PD	196
IgG	Patient 3	4	mild	G75896PD	175
IgM	Patient 3	11	mild	G75896PD	405
IgM	Patient 3	4	mild	G75896PD	404
IgA	Patient 4	12	mild	G75896PD	988
IgG	Patient 4	12	mild	G75896PD	365
IgM	Patient 4	12	mild	G75896PD	2119
IgA	Patient 1	10	moderate	G76355TG	375
IgA	Patient 1	22	moderate	G76355TG	392
IgA	Patient 1	6	moderate	G76355TG	375
IgG	Patient 1	10	moderate	G76355TG	22
IgG	Patient 1	22	moderate	G76355TG	25
IgM	Patient 1	10	moderate	G76355TG	46
IgM	Patient 1	22	moderate	G76355TG	58
IgG	Patient 1	6	moderate	G76355TG	28
IgM	Patient 1	6	moderate	G76355TG	57
IgA	Patient 2	15	mild	G76355TG	1163