GlyCosmos Portal

GlyCOVID

GlyCOVID is a dataset of RDFized COVID-19 data related to glycans. Resources will be added incrementally as publications are curated.

Longitudinal Development of Antibody Responses in COVID-19 Patients of Different Severity with ELISA, Peptide, and Glycan Arrays: An Immunological Case Series.
Heidepriem J, et al.
Pathogens. 2021; 10(4):438. https://doi.org/10.3390/pathogens10040438

A longitudinal analysis of three COVID-19 patients with moderate (#1) and mild disease (#2 and #3) was published. Antibody serum responses were analyzed using spike glycoprotein enzyme linked immunosorbent assay (ELISA), full-proteome peptide, and glycan microarrays. In this Glycovid dataset, the data from these glycan microarray experiments have been RDFized. Fluorescence intensity is given in arbitrary fluorescence units (AFU) as reported in this publication.

Source	Last Updated
PSICQUIC	March 30, 2022

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Antibody	Patient	Onset (days)	Symptom	GlyTouCan ID ▲	Arbitrary Fluorescence Units (AFU)
IgA	Patient 2	24	mild	G76355TG	1279
IgG	Patient 2	15	mild	G76355TG	207
IgG	Patient 2	24	mild	G76355TG	210
IgM	Patient 2	15	mild	G76355TG	2231
IgM	Patient 2	24	mild	G76355TG	2417
IgA	Patient 2	3	mild	G76355TG	538
IgG	Patient 2	3	mild	G76355TG	43
IgM	Patient 2	3	mild	G76355TG	112
IgA	Patient 3	-180	mild	G76355TG	278
IgA	Patient 3	11	mild	G76355TG	398
IgG	Patient 3	-180	mild	G76355TG	58
IgM	Patient 3	-180	mild	G76355TG	110
IgA	Patient 3	4	mild	G76355TG	407
IgG	Patient 3	11	mild	G76355TG	47
IgG	Patient 3	4	mild	G76355TG	49
IgM	Patient 3	11	mild	G76355TG	129
IgM	Patient 3	4	mild	G76355TG	139
IgA	Patient 4	12	mild	G76355TG	1683
IgG	Patient 4	12	mild	G76355TG	447
IgM	Patient 4	12	mild	G76355TG	4331
IgA	Patient 1	10	moderate	G76615YG	337
IgA	Patient 1	22	moderate	G76615YG	324
IgA	Patient 1	6	moderate	G76615YG	339
IgG	Patient 1	10	moderate	G76615YG	23
IgG	Patient 1	22	moderate	G76615YG	34