GlyCosmos Portal

GlyCOVID

GlyCOVID is a dataset of RDFized COVID-19 data related to glycans. Resources will be added incrementally as publications are curated.

Longitudinal Development of Antibody Responses in COVID-19 Patients of Different Severity with ELISA, Peptide, and Glycan Arrays: An Immunological Case Series.
Heidepriem J, et al.
Pathogens. 2021; 10(4):438. https://doi.org/10.3390/pathogens10040438

A longitudinal analysis of three COVID-19 patients with moderate (#1) and mild disease (#2 and #3) was published. Antibody serum responses were analyzed using spike glycoprotein enzyme linked immunosorbent assay (ELISA), full-proteome peptide, and glycan microarrays. In this Glycovid dataset, the data from these glycan microarray experiments have been RDFized. Fluorescence intensity is given in arbitrary fluorescence units (AFU) as reported in this publication.

Source	Last Updated
PSICQUIC	March 30, 2022

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Antibody	Patient	Onset (days)	Symptom	GlyTouCan ID ▲	Arbitrary Fluorescence Units (AFU)
IgA	Patient 1	10	moderate	G82096UQ	393
IgA	Patient 1	22	moderate	G82096UQ	343
IgA	Patient 1	6	moderate	G82096UQ	399
IgG	Patient 1	10	moderate	G82096UQ	27
IgG	Patient 1	22	moderate	G82096UQ	28
IgM	Patient 1	10	moderate	G82096UQ	35
IgM	Patient 1	22	moderate	G82096UQ	45
IgG	Patient 1	6	moderate	G82096UQ	27
IgM	Patient 1	6	moderate	G82096UQ	34
IgA	Patient 2	15	mild	G82096UQ	414
IgA	Patient 2	24	mild	G82096UQ	453
IgG	Patient 2	15	mild	G82096UQ	60
IgG	Patient 2	24	mild	G82096UQ	65
IgM	Patient 2	15	mild	G82096UQ	273
IgA	Patient 2	3	mild	G82096UQ	440
IgG	Patient 2	3	mild	G82096UQ	69
IgM	Patient 2	24	mild	G82096UQ	336
IgM	Patient 2	3	mild	G82096UQ	344
IgA	Patient 3	-180	mild	G82096UQ	319
IgA	Patient 3	11	mild	G82096UQ	621
IgG	Patient 3	-180	mild	G82096UQ	68
IgM	Patient 3	-180	mild	G82096UQ	229
IgA	Patient 3	4	mild	G82096UQ	667
IgG	Patient 3	11	mild	G82096UQ	144
IgG	Patient 3	4	mild	G82096UQ	146