GlyCosmos Portal

GlyCOVID

GlyCOVID is a dataset of RDFized COVID-19 data related to glycans. Resources will be added incrementally as publications are curated.

Longitudinal Development of Antibody Responses in COVID-19 Patients of Different Severity with ELISA, Peptide, and Glycan Arrays: An Immunological Case Series.
Heidepriem J, et al.
Pathogens. 2021; 10(4):438. https://doi.org/10.3390/pathogens10040438

A longitudinal analysis of three COVID-19 patients with moderate (#1) and mild disease (#2 and #3) was published. Antibody serum responses were analyzed using spike glycoprotein enzyme linked immunosorbent assay (ELISA), full-proteome peptide, and glycan microarrays. In this Glycovid dataset, the data from these glycan microarray experiments have been RDFized. Fluorescence intensity is given in arbitrary fluorescence units (AFU) as reported in this publication.

Source	Last Updated
PSICQUIC	March 30, 2022

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Antibody	Patient	Onset (days)	Symptom	GlyTouCan ID ▲	Arbitrary Fluorescence Units (AFU)
IgA	Patient 1	10	moderate	G84224TW	358
IgA	Patient 1	22	moderate	G84224TW	325
IgA	Patient 1	6	moderate	G84224TW	312
IgG	Patient 1	10	moderate	G84224TW	27
IgG	Patient 1	22	moderate	G84224TW	36
IgM	Patient 1	10	moderate	G84224TW	36
IgM	Patient 1	22	moderate	G84224TW	47
IgG	Patient 1	6	moderate	G84224TW	28
IgM	Patient 1	6	moderate	G84224TW	34
IgA	Patient 2	15	mild	G84224TW	344
IgA	Patient 2	24	mild	G84224TW	525
IgG	Patient 2	15	mild	G84224TW	73
IgG	Patient 2	24	mild	G84224TW	105
IgM	Patient 2	15	mild	G84224TW	72
IgA	Patient 2	3	mild	G84224TW	553
IgG	Patient 2	3	mild	G84224TW	127
IgM	Patient 2	24	mild	G84224TW	75
IgM	Patient 2	3	mild	G84224TW	93
IgA	Patient 3	-180	mild	G84224TW	302
IgA	Patient 3	11	mild	G84224TW	569
IgG	Patient 3	-180	mild	G84224TW	56
IgM	Patient 3	-180	mild	G84224TW	150
IgA	Patient 3	4	mild	G84224TW	512
IgG	Patient 3	11	mild	G84224TW	149
IgG	Patient 3	4	mild	G84224TW	123