GlyCosmos Portal

GlyCOVID

GlyCOVID is a dataset of RDFized COVID-19 data related to glycans. Resources will be added incrementally as publications are curated.

Longitudinal Development of Antibody Responses in COVID-19 Patients of Different Severity with ELISA, Peptide, and Glycan Arrays: An Immunological Case Series.
Heidepriem J, et al.
Pathogens. 2021; 10(4):438. https://doi.org/10.3390/pathogens10040438

A longitudinal analysis of three COVID-19 patients with moderate (#1) and mild disease (#2 and #3) was published. Antibody serum responses were analyzed using spike glycoprotein enzyme linked immunosorbent assay (ELISA), full-proteome peptide, and glycan microarrays. In this Glycovid dataset, the data from these glycan microarray experiments have been RDFized. Fluorescence intensity is given in arbitrary fluorescence units (AFU) as reported in this publication.

Source	Last Updated
PSICQUIC	March 30, 2022

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Antibody	Patient	Onset (days)	Symptom	GlyTouCan ID ▲	Arbitrary Fluorescence Units (AFU)
IgM	Patient 3	11	mild	G84224TW	388
IgM	Patient 3	4	mild	G84224TW	332
IgA	Patient 4	12	mild	G84224TW	555
IgG	Patient 4	12	mild	G84224TW	110
IgM	Patient 4	12	mild	G84224TW	357
IgA	Patient 1	10	moderate	G86156UJ	311
IgA	Patient 1	22	moderate	G86156UJ	438
IgA	Patient 1	6	moderate	G86156UJ	448
IgG	Patient 1	10	moderate	G86156UJ	50
IgG	Patient 1	22	moderate	G86156UJ	75
IgM	Patient 1	10	moderate	G86156UJ	48
IgM	Patient 1	22	moderate	G86156UJ	190
IgG	Patient 1	6	moderate	G86156UJ	59
IgM	Patient 1	6	moderate	G86156UJ	48
IgA	Patient 2	15	mild	G86156UJ	450
IgA	Patient 2	24	mild	G86156UJ	544
IgG	Patient 2	15	mild	G86156UJ	11027
IgG	Patient 2	24	mild	G86156UJ	11808
IgM	Patient 2	15	mild	G86156UJ	284
IgA	Patient 2	3	mild	G86156UJ	672
IgG	Patient 2	3	mild	G86156UJ	22997
IgM	Patient 2	24	mild	G86156UJ	331
IgM	Patient 2	3	mild	G86156UJ	527
IgA	Patient 3	-180	mild	G86156UJ	256
IgA	Patient 3	11	mild	G86156UJ	442