GlyCosmos Portal

GlyCOVID

GlyCOVID is a dataset of RDFized COVID-19 data related to glycans. Resources will be added incrementally as publications are curated.

Longitudinal Development of Antibody Responses in COVID-19 Patients of Different Severity with ELISA, Peptide, and Glycan Arrays: An Immunological Case Series.
Heidepriem J, et al.
Pathogens. 2021; 10(4):438. https://doi.org/10.3390/pathogens10040438

A longitudinal analysis of three COVID-19 patients with moderate (#1) and mild disease (#2 and #3) was published. Antibody serum responses were analyzed using spike glycoprotein enzyme linked immunosorbent assay (ELISA), full-proteome peptide, and glycan microarrays. In this Glycovid dataset, the data from these glycan microarray experiments have been RDFized. Fluorescence intensity is given in arbitrary fluorescence units (AFU) as reported in this publication.

Source	Last Updated
PSICQUIC	March 30, 2022

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Antibody	Patient	Onset (days)	Symptom	GlyTouCan ID ▼	Arbitrary Fluorescence Units (AFU)
IgM	Patient 3	11	mild	G11460AB	7368
IgM	Patient 3	4	mild	G11460AB	8254
IgA	Patient 4	12	mild	G11460AB	451
IgG	Patient 4	12	mild	G11460AB	196
IgM	Patient 4	12	mild	G11460AB	350
IgA	Patient 1	10	moderate	G10789DJ	287
IgA	Patient 1	22	moderate	G10789DJ	416
IgA	Patient 1	6	moderate	G10789DJ	398
IgG	Patient 1	10	moderate	G10789DJ	26
IgG	Patient 1	22	moderate	G10789DJ	34
IgG	Patient 1	6	moderate	G10789DJ	25
IgM	Patient 1	10	moderate	G10789DJ	44
IgM	Patient 1	22	moderate	G10789DJ	119
IgM	Patient 1	6	moderate	G10789DJ	49
IgA	Patient 2	15	mild	G10789DJ	496
IgA	Patient 2	24	mild	G10789DJ	594
IgG	Patient 2	15	mild	G10789DJ	531
IgG	Patient 2	24	mild	G10789DJ	580
IgM	Patient 2	15	mild	G10789DJ	181
IgM	Patient 2	24	mild	G10789DJ	210
IgA	Patient 2	3	mild	G10789DJ	557
IgG	Patient 2	3	mild	G10789DJ	710
IgM	Patient 2	3	mild	G10789DJ	241
IgA	Patient 3	-180	mild	G10789DJ	272
IgA	Patient 3	11	mild	G10789DJ	441