GlyCosmos Portal

GlyCOVID

GlyCOVID is a dataset of RDFized COVID-19 data related to glycans. Resources will be added incrementally as publications are curated.

Longitudinal Development of Antibody Responses in COVID-19 Patients of Different Severity with ELISA, Peptide, and Glycan Arrays: An Immunological Case Series.
Heidepriem J, et al.
Pathogens. 2021; 10(4):438. https://doi.org/10.3390/pathogens10040438

A longitudinal analysis of three COVID-19 patients with moderate (#1) and mild disease (#2 and #3) was published. Antibody serum responses were analyzed using spike glycoprotein enzyme linked immunosorbent assay (ELISA), full-proteome peptide, and glycan microarrays. In this Glycovid dataset, the data from these glycan microarray experiments have been RDFized. Fluorescence intensity is given in arbitrary fluorescence units (AFU) as reported in this publication.

Source	Last Updated
PSICQUIC	March 30, 2022

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Antibody	Patient	Onset (days)	Symptom	GlyTouCan ID ▲	Arbitrary Fluorescence Units (AFU)
IgG	Patient 3	-180	mild	G03499BP	50
IgG	Patient 3	11	mild	G03499BP	68
IgM	Patient 3	-180	mild	G03499BP	100
IgA	Patient 3	4	mild	G03499BP	468
IgG	Patient 3	4	mild	G03499BP	76
IgM	Patient 3	11	mild	G03499BP	250
IgM	Patient 3	4	mild	G03499BP	337
IgA	Patient 4	12	mild	G03499BP	401
IgG	Patient 4	12	mild	G03499BP	118
IgM	Patient 4	12	mild	G03499BP	207
IgA	Patient 1	10	moderate	G07483YN	427
IgA	Patient 1	22	moderate	G07483YN	429
IgA	Patient 1	6	moderate	G07483YN	315
IgG	Patient 1	10	moderate	G07483YN	25
IgG	Patient 1	22	moderate	G07483YN	34
IgG	Patient 1	6	moderate	G07483YN	26
IgM	Patient 1	10	moderate	G07483YN	48
IgM	Patient 1	22	moderate	G07483YN	182
IgM	Patient 1	6	moderate	G07483YN	45
IgA	Patient 2	15	mild	G07483YN	343
IgA	Patient 2	24	mild	G07483YN	343
IgG	Patient 2	15	mild	G07483YN	31
IgG	Patient 2	24	mild	G07483YN	30
IgM	Patient 2	15	mild	G07483YN	91
IgM	Patient 2	24	mild	G07483YN	84