GlyCosmos Portal

GlyCOVID

GlyCOVID is a dataset of RDFized COVID-19 data related to glycans. Resources will be added incrementally as publications are curated.

Longitudinal Development of Antibody Responses in COVID-19 Patients of Different Severity with ELISA, Peptide, and Glycan Arrays: An Immunological Case Series.
Heidepriem J, et al.
Pathogens. 2021; 10(4):438. https://doi.org/10.3390/pathogens10040438

A longitudinal analysis of three COVID-19 patients with moderate (#1) and mild disease (#2 and #3) was published. Antibody serum responses were analyzed using spike glycoprotein enzyme linked immunosorbent assay (ELISA), full-proteome peptide, and glycan microarrays. In this Glycovid dataset, the data from these glycan microarray experiments have been RDFized. Fluorescence intensity is given in arbitrary fluorescence units (AFU) as reported in this publication.

Source	Last Updated
PSICQUIC	March 30, 2022

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Antibody	Patient	Onset (days)	Symptom	GlyTouCan ID ▲	Arbitrary Fluorescence Units (AFU)
IgG	Patient 3	-180	mild	G93351GM	39
IgM	Patient 3	-180	mild	G93351GM	74
IgA	Patient 3	4	mild	G93351GM	500
IgG	Patient 3	11	mild	G93351GM	47
IgG	Patient 3	4	mild	G93351GM	49
IgM	Patient 3	11	mild	G93351GM	103
IgM	Patient 3	4	mild	G93351GM	121
IgA	Patient 4	12	mild	G93351GM	372
IgG	Patient 4	12	mild	G93351GM	50
IgM	Patient 4	12	mild	G93351GM	82
IgA	Patient 1	10	moderate	G94435QH	361
IgA	Patient 1	22	moderate	G94435QH	364
IgA	Patient 1	6	moderate	G94435QH	347
IgG	Patient 1	10	moderate	G94435QH	21
IgG	Patient 1	22	moderate	G94435QH	22
IgM	Patient 1	10	moderate	G94435QH	34
IgM	Patient 1	22	moderate	G94435QH	30
IgG	Patient 1	6	moderate	G94435QH	26
IgM	Patient 1	6	moderate	G94435QH	34
IgA	Patient 2	15	mild	G94435QH	285
IgA	Patient 2	24	mild	G94435QH	343
IgG	Patient 2	15	mild	G94435QH	102
IgG	Patient 2	24	mild	G94435QH	115
IgM	Patient 2	15	mild	G94435QH	56
IgA	Patient 2	3	mild	G94435QH	282