GlyCosmos Portal

GlyCOVID

GlyCOVID is a dataset of RDFized COVID-19 data related to glycans. Resources will be added incrementally as publications are curated.

Longitudinal Development of Antibody Responses in COVID-19 Patients of Different Severity with ELISA, Peptide, and Glycan Arrays: An Immunological Case Series.
Heidepriem J, et al.
Pathogens. 2021; 10(4):438. https://doi.org/10.3390/pathogens10040438

A longitudinal analysis of three COVID-19 patients with moderate (#1) and mild disease (#2 and #3) was published. Antibody serum responses were analyzed using spike glycoprotein enzyme linked immunosorbent assay (ELISA), full-proteome peptide, and glycan microarrays. In this Glycovid dataset, the data from these glycan microarray experiments have been RDFized. Fluorescence intensity is given in arbitrary fluorescence units (AFU) as reported in this publication.

Source	Last Updated
PSICQUIC	March 30, 2022

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Antibody	Patient	Onset (days)	Symptom	GlyTouCan ID ▲	Arbitrary Fluorescence Units (AFU)
IgA	Patient 2	24	mild	G08340FW	411
IgG	Patient 2	15	mild	G08340FW	6474
IgG	Patient 2	24	mild	G08340FW	6617
IgM	Patient 2	15	mild	G08340FW	131
IgM	Patient 2	24	mild	G08340FW	144
IgA	Patient 2	3	mild	G08340FW	477
IgG	Patient 2	3	mild	G08340FW	12949
IgM	Patient 2	3	mild	G08340FW	216
IgA	Patient 3	-180	mild	G08340FW	3386
IgA	Patient 3	11	mild	G08340FW	3668
IgG	Patient 3	-180	mild	G08340FW	2275
IgG	Patient 3	11	mild	G08340FW	2878
IgM	Patient 3	-180	mild	G08340FW	9975
IgA	Patient 3	4	mild	G08340FW	3027
IgG	Patient 3	4	mild	G08340FW	2573
IgM	Patient 3	11	mild	G08340FW	10921
IgM	Patient 3	4	mild	G08340FW	9694
IgA	Patient 4	12	mild	G08340FW	494
IgG	Patient 4	12	mild	G08340FW	235
IgM	Patient 4	12	mild	G08340FW	448
IgA	Patient 1	10	moderate	G08520NM	430
IgA	Patient 1	22	moderate	G08520NM	394
IgA	Patient 1	6	moderate	G08520NM	409
IgG	Patient 1	10	moderate	G08520NM	24
IgG	Patient 1	22	moderate	G08520NM	38