GlyCosmos Portal

GlyCOVID

GlyCOVID is a dataset of RDFized COVID-19 data related to glycans. Resources will be added incrementally as publications are curated.

Longitudinal Development of Antibody Responses in COVID-19 Patients of Different Severity with ELISA, Peptide, and Glycan Arrays: An Immunological Case Series.
Heidepriem J, et al.
Pathogens. 2021; 10(4):438. https://doi.org/10.3390/pathogens10040438

A longitudinal analysis of three COVID-19 patients with moderate (#1) and mild disease (#2 and #3) was published. Antibody serum responses were analyzed using spike glycoprotein enzyme linked immunosorbent assay (ELISA), full-proteome peptide, and glycan microarrays. In this Glycovid dataset, the data from these glycan microarray experiments have been RDFized. Fluorescence intensity is given in arbitrary fluorescence units (AFU) as reported in this publication.

Source	Last Updated
PSICQUIC	March 30, 2022

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Antibody	Patient	Onset (days)	Symptom	GlyTouCan ID ▲	Arbitrary Fluorescence Units (AFU)
IgA	Patient 2	3	mild	G10133VD	867
IgG	Patient 2	3	mild	G10133VD	115
IgM	Patient 2	3	mild	G10133VD	714
IgA	Patient 3	-180	mild	G10133VD	290
IgA	Patient 3	11	mild	G10133VD	489
IgG	Patient 3	-180	mild	G10133VD	54
IgG	Patient 3	11	mild	G10133VD	95
IgM	Patient 3	-180	mild	G10133VD	109
IgA	Patient 3	4	mild	G10133VD	426
IgG	Patient 3	4	mild	G10133VD	63
IgM	Patient 3	11	mild	G10133VD	509
IgM	Patient 3	4	mild	G10133VD	218
IgA	Patient 4	12	mild	G10133VD	2453
IgG	Patient 4	12	mild	G10133VD	606
IgM	Patient 4	12	mild	G10133VD	5152
IgA	Patient 1	10	moderate	G10789DJ	287
IgA	Patient 1	22	moderate	G10789DJ	416
IgA	Patient 1	6	moderate	G10789DJ	398
IgG	Patient 1	10	moderate	G10789DJ	26
IgG	Patient 1	22	moderate	G10789DJ	34
IgG	Patient 1	6	moderate	G10789DJ	25
IgM	Patient 1	10	moderate	G10789DJ	44
IgM	Patient 1	22	moderate	G10789DJ	119
IgM	Patient 1	6	moderate	G10789DJ	49
IgA	Patient 2	15	mild	G10789DJ	496