GlyCosmos Portal

GlyCOVID

GlyCOVID is a dataset of RDFized COVID-19 data related to glycans. Resources will be added incrementally as publications are curated.

Longitudinal Development of Antibody Responses in COVID-19 Patients of Different Severity with ELISA, Peptide, and Glycan Arrays: An Immunological Case Series.
Heidepriem J, et al.
Pathogens. 2021; 10(4):438. https://doi.org/10.3390/pathogens10040438

A longitudinal analysis of three COVID-19 patients with moderate (#1) and mild disease (#2 and #3) was published. Antibody serum responses were analyzed using spike glycoprotein enzyme linked immunosorbent assay (ELISA), full-proteome peptide, and glycan microarrays. In this Glycovid dataset, the data from these glycan microarray experiments have been RDFized. Fluorescence intensity is given in arbitrary fluorescence units (AFU) as reported in this publication.

Source	Last Updated
PSICQUIC	March 30, 2022

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Antibody	Patient	Onset (days)	Symptom	GlyTouCan ID ▲	Arbitrary Fluorescence Units (AFU)
IgG	Patient 3	-180	mild	G14569AR	3411
IgG	Patient 3	11	mild	G14569AR	4454
IgM	Patient 3	-180	mild	G14569AR	6735
IgA	Patient 3	4	mild	G14569AR	2901
IgG	Patient 3	4	mild	G14569AR	4766
IgM	Patient 3	11	mild	G14569AR	8027
IgM	Patient 3	4	mild	G14569AR	8558
IgA	Patient 4	12	mild	G14569AR	406
IgG	Patient 4	12	mild	G14569AR	84
IgM	Patient 4	12	mild	G14569AR	99
IgA	Patient 1	10	moderate	G14844CX	414
IgA	Patient 1	22	moderate	G14844CX	389
IgA	Patient 1	6	moderate	G14844CX	303
IgG	Patient 1	10	moderate	G14844CX	27
IgG	Patient 1	22	moderate	G14844CX	35
IgG	Patient 1	6	moderate	G14844CX	24
IgM	Patient 1	10	moderate	G14844CX	57
IgM	Patient 1	22	moderate	G14844CX	174
IgM	Patient 1	6	moderate	G14844CX	38
IgA	Patient 2	15	mild	G14844CX	327
IgA	Patient 2	24	mild	G14844CX	368
IgG	Patient 2	15	mild	G14844CX	31
IgG	Patient 2	24	mild	G14844CX	37
IgM	Patient 2	15	mild	G14844CX	98
IgM	Patient 2	24	mild	G14844CX	131