GlyCosmos Portal

GlyCOVID

GlyCOVID is a dataset of RDFized COVID-19 data related to glycans. Resources will be added incrementally as publications are curated.

Longitudinal Development of Antibody Responses in COVID-19 Patients of Different Severity with ELISA, Peptide, and Glycan Arrays: An Immunological Case Series.
Heidepriem J, et al.
Pathogens. 2021; 10(4):438. https://doi.org/10.3390/pathogens10040438

A longitudinal analysis of three COVID-19 patients with moderate (#1) and mild disease (#2 and #3) was published. Antibody serum responses were analyzed using spike glycoprotein enzyme linked immunosorbent assay (ELISA), full-proteome peptide, and glycan microarrays. In this Glycovid dataset, the data from these glycan microarray experiments have been RDFized. Fluorescence intensity is given in arbitrary fluorescence units (AFU) as reported in this publication.

Source	Last Updated
PSICQUIC	March 30, 2022

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Antibody	Patient	Onset (days)	Symptom	GlyTouCan ID ▲	Arbitrary Fluorescence Units (AFU)
IgA	Patient 2	3	mild	G14844CX	354
IgG	Patient 2	3	mild	G14844CX	46
IgM	Patient 2	3	mild	G14844CX	169
IgA	Patient 3	-180	mild	G14844CX	265
IgA	Patient 3	11	mild	G14844CX	362
IgG	Patient 3	-180	mild	G14844CX	53
IgG	Patient 3	11	mild	G14844CX	45
IgM	Patient 3	-180	mild	G14844CX	91
IgA	Patient 3	4	mild	G14844CX	374
IgG	Patient 3	4	mild	G14844CX	42
IgM	Patient 3	11	mild	G14844CX	104
IgM	Patient 3	4	mild	G14844CX	94
IgA	Patient 4	12	mild	G14844CX	1193
IgG	Patient 4	12	mild	G14844CX	295
IgM	Patient 4	12	mild	G14844CX	2240
IgA	Patient 1	10	moderate	G14988WV	410
IgA	Patient 1	22	moderate	G14988WV	450
IgA	Patient 1	6	moderate	G14988WV	290
IgG	Patient 1	10	moderate	G14988WV	34
IgG	Patient 1	22	moderate	G14988WV	49
IgG	Patient 1	6	moderate	G14988WV	25
IgM	Patient 1	10	moderate	G14988WV	69
IgM	Patient 1	22	moderate	G14988WV	220
IgM	Patient 1	6	moderate	G14988WV	42
IgA	Patient 2	15	mild	G14988WV	380