GlyCosmos Portal

GlyCOVID

GlyCOVID is a dataset of RDFized COVID-19 data related to glycans. Resources will be added incrementally as publications are curated.

Longitudinal Development of Antibody Responses in COVID-19 Patients of Different Severity with ELISA, Peptide, and Glycan Arrays: An Immunological Case Series.
Heidepriem J, et al.
Pathogens. 2021; 10(4):438. https://doi.org/10.3390/pathogens10040438

A longitudinal analysis of three COVID-19 patients with moderate (#1) and mild disease (#2 and #3) was published. Antibody serum responses were analyzed using spike glycoprotein enzyme linked immunosorbent assay (ELISA), full-proteome peptide, and glycan microarrays. In this Glycovid dataset, the data from these glycan microarray experiments have been RDFized. Fluorescence intensity is given in arbitrary fluorescence units (AFU) as reported in this publication.

Source	Last Updated
PSICQUIC	March 30, 2022

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Antibody	Patient	Onset (days)	Symptom	GlyTouCan ID ▲	Arbitrary Fluorescence Units (AFU)
IgA	Patient 2	24	mild	G14988WV	385
IgG	Patient 2	15	mild	G14988WV	162
IgG	Patient 2	24	mild	G14988WV	164
IgM	Patient 2	15	mild	G14988WV	203
IgM	Patient 2	24	mild	G14988WV	233
IgA	Patient 2	3	mild	G14988WV	371
IgG	Patient 2	3	mild	G14988WV	181
IgM	Patient 2	3	mild	G14988WV	255
IgA	Patient 3	-180	mild	G14988WV	279
IgA	Patient 3	11	mild	G14988WV	450
IgG	Patient 3	-180	mild	G14988WV	48
IgG	Patient 3	11	mild	G14988WV	115
IgM	Patient 3	-180	mild	G14988WV	87
IgA	Patient 3	4	mild	G14988WV	527
IgG	Patient 3	4	mild	G14988WV	120
IgM	Patient 3	11	mild	G14988WV	372
IgM	Patient 3	4	mild	G14988WV	423
IgA	Patient 4	12	mild	G14988WV	621
IgG	Patient 4	12	mild	G14988WV	253
IgM	Patient 4	12	mild	G14988WV	808
IgA	Patient 1	10	moderate	G15209MJ	406
IgA	Patient 1	22	moderate	G15209MJ	426
IgA	Patient 1	6	moderate	G15209MJ	362
IgG	Patient 1	10	moderate	G15209MJ	25
IgG	Patient 1	22	moderate	G15209MJ	32