GlyCosmos Portal

GlyCOVID

GlyCOVID is a dataset of RDFized COVID-19 data related to glycans. Resources will be added incrementally as publications are curated.

Longitudinal Development of Antibody Responses in COVID-19 Patients of Different Severity with ELISA, Peptide, and Glycan Arrays: An Immunological Case Series.
Heidepriem J, et al.
Pathogens. 2021; 10(4):438. https://doi.org/10.3390/pathogens10040438

A longitudinal analysis of three COVID-19 patients with moderate (#1) and mild disease (#2 and #3) was published. Antibody serum responses were analyzed using spike glycoprotein enzyme linked immunosorbent assay (ELISA), full-proteome peptide, and glycan microarrays. In this Glycovid dataset, the data from these glycan microarray experiments have been RDFized. Fluorescence intensity is given in arbitrary fluorescence units (AFU) as reported in this publication.

Source	Last Updated
PSICQUIC	March 30, 2022

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Antibody	Patient	Onset (days)	Symptom	GlyTouCan ID ▲	Arbitrary Fluorescence Units (AFU)
IgA	Patient 2	3	mild	G17140UR	576
IgG	Patient 2	3	mild	G17140UR	90
IgM	Patient 2	3	mild	G17140UR	690
IgA	Patient 3	-180	mild	G17140UR	326
IgA	Patient 3	11	mild	G17140UR	470
IgG	Patient 3	-180	mild	G17140UR	73
IgG	Patient 3	11	mild	G17140UR	124
IgM	Patient 3	-180	mild	G17140UR	155
IgA	Patient 3	4	mild	G17140UR	469
IgG	Patient 3	4	mild	G17140UR	105
IgM	Patient 3	11	mild	G17140UR	301
IgM	Patient 3	4	mild	G17140UR	274
IgA	Patient 4	12	mild	G17140UR	865
IgG	Patient 4	12	mild	G17140UR	274
IgM	Patient 4	12	mild	G17140UR	1716
IgA	Patient 1	10	moderate	G17266GE	348
IgA	Patient 1	22	moderate	G17266GE	350
IgA	Patient 1	6	moderate	G17266GE	338
IgG	Patient 1	10	moderate	G17266GE	22
IgG	Patient 1	22	moderate	G17266GE	23
IgG	Patient 1	6	moderate	G17266GE	25
IgM	Patient 1	10	moderate	G17266GE	36
IgM	Patient 1	22	moderate	G17266GE	38
IgM	Patient 1	6	moderate	G17266GE	30
IgA	Patient 2	15	mild	G17266GE	352