GlyCosmos Portal

GlyCOVID

GlyCOVID is a dataset of RDFized COVID-19 data related to glycans. Resources will be added incrementally as publications are curated.

Longitudinal Development of Antibody Responses in COVID-19 Patients of Different Severity with ELISA, Peptide, and Glycan Arrays: An Immunological Case Series.
Heidepriem J, et al.
Pathogens. 2021; 10(4):438. https://doi.org/10.3390/pathogens10040438

A longitudinal analysis of three COVID-19 patients with moderate (#1) and mild disease (#2 and #3) was published. Antibody serum responses were analyzed using spike glycoprotein enzyme linked immunosorbent assay (ELISA), full-proteome peptide, and glycan microarrays. In this Glycovid dataset, the data from these glycan microarray experiments have been RDFized. Fluorescence intensity is given in arbitrary fluorescence units (AFU) as reported in this publication.

Source	Last Updated
PSICQUIC	March 30, 2022

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Antibody	Patient	Onset (days)	Symptom	GlyTouCan ID ▲	Arbitrary Fluorescence Units (AFU)
IgG	Patient 3	-180	mild	G18057VI	54
IgM	Patient 3	-180	mild	G18057VI	95
IgA	Patient 3	4	mild	G18057VI	449
IgG	Patient 3	11	mild	G18057VI	45
IgG	Patient 3	4	mild	G18057VI	44
IgM	Patient 3	11	mild	G18057VI	106
IgM	Patient 3	4	mild	G18057VI	94
IgA	Patient 4	12	mild	G18057VI	387
IgG	Patient 4	12	mild	G18057VI	100
IgM	Patient 4	12	mild	G18057VI	157
IgA	Patient 1	10	moderate	G19118WX	402
IgA	Patient 1	22	moderate	G19118WX	378
IgA	Patient 1	6	moderate	G19118WX	328
IgG	Patient 1	10	moderate	G19118WX	38
IgG	Patient 1	22	moderate	G19118WX	34
IgG	Patient 1	6	moderate	G19118WX	28
IgM	Patient 1	10	moderate	G19118WX	37
IgM	Patient 1	22	moderate	G19118WX	38
IgM	Patient 1	6	moderate	G19118WX	31
IgA	Patient 2	15	mild	G19118WX	434
IgA	Patient 2	24	mild	G19118WX	517
IgG	Patient 2	15	mild	G19118WX	14625
IgG	Patient 2	24	mild	G19118WX	16932
IgM	Patient 2	15	mild	G19118WX	195
IgM	Patient 2	24	mild	G19118WX	238