GlyCosmos Portal

GlyCOVID

GlyCOVID is a dataset of RDFized COVID-19 data related to glycans. Resources will be added incrementally as publications are curated.

Longitudinal Development of Antibody Responses in COVID-19 Patients of Different Severity with ELISA, Peptide, and Glycan Arrays: An Immunological Case Series.
Heidepriem J, et al.
Pathogens. 2021; 10(4):438. https://doi.org/10.3390/pathogens10040438

A longitudinal analysis of three COVID-19 patients with moderate (#1) and mild disease (#2 and #3) was published. Antibody serum responses were analyzed using spike glycoprotein enzyme linked immunosorbent assay (ELISA), full-proteome peptide, and glycan microarrays. In this Glycovid dataset, the data from these glycan microarray experiments have been RDFized. Fluorescence intensity is given in arbitrary fluorescence units (AFU) as reported in this publication.

Source	Last Updated
PSICQUIC	March 30, 2022

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Antibody	Patient	Onset (days)	Symptom	GlyTouCan ID ▲	Arbitrary Fluorescence Units (AFU)
IgA	Patient 2	3	mild	G00052MO	284
IgG	Patient 2	3	mild	G00052MO	28
IgM	Patient 2	3	mild	G00052MO	46
IgA	Patient 3	-180	mild	G00052MO	275
IgA	Patient 3	11	mild	G00052MO	386
IgG	Patient 3	-180	mild	G00052MO	47
IgG	Patient 3	11	mild	G00052MO	52
IgM	Patient 3	-180	mild	G00052MO	94
IgA	Patient 3	4	mild	G00052MO	450
IgG	Patient 3	4	mild	G00052MO	52
IgM	Patient 3	11	mild	G00052MO	128
IgM	Patient 3	4	mild	G00052MO	140
IgA	Patient 4	12	mild	G00052MO	371
IgG	Patient 4	12	mild	G00052MO	101
IgM	Patient 4	12	mild	G00052MO	178
IgA	Patient 1	10	moderate	G00053MO	329
IgA	Patient 1	22	moderate	G00053MO	318
IgA	Patient 1	6	moderate	G00053MO	203
IgG	Patient 1	10	moderate	G00053MO	23
IgG	Patient 1	22	moderate	G00053MO	22
IgG	Patient 1	6	moderate	G00053MO	26
IgM	Patient 1	10	moderate	G00053MO	32
IgM	Patient 1	22	moderate	G00053MO	38
IgM	Patient 1	6	moderate	G00053MO	47
IgA	Patient 2	15	mild	G00053MO	268