GlyCosmos Portal

GlyCOVID

GlyCOVID is a dataset of RDFized COVID-19 data related to glycans. Resources will be added incrementally as publications are curated.

Longitudinal Development of Antibody Responses in COVID-19 Patients of Different Severity with ELISA, Peptide, and Glycan Arrays: An Immunological Case Series.
Heidepriem J, et al.
Pathogens. 2021; 10(4):438. https://doi.org/10.3390/pathogens10040438

A longitudinal analysis of three COVID-19 patients with moderate (#1) and mild disease (#2 and #3) was published. Antibody serum responses were analyzed using spike glycoprotein enzyme linked immunosorbent assay (ELISA), full-proteome peptide, and glycan microarrays. In this Glycovid dataset, the data from these glycan microarray experiments have been RDFized. Fluorescence intensity is given in arbitrary fluorescence units (AFU) as reported in this publication.

Source	Last Updated
PSICQUIC	March 30, 2022

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Antibody	Patient	Onset (days)	Symptom	GlyTouCan ID ▲	Arbitrary Fluorescence Units (AFU)
IgA	Patient 2	3	mild	G19118WX	569
IgG	Patient 2	3	mild	G19118WX	23027
IgM	Patient 2	3	mild	G19118WX	273
IgA	Patient 3	-180	mild	G19118WX	3115
IgA	Patient 3	11	mild	G19118WX	3595
IgG	Patient 3	-180	mild	G19118WX	24795
IgM	Patient 3	-180	mild	G19118WX	8125
IgA	Patient 3	4	mild	G19118WX	3902
IgG	Patient 3	11	mild	G19118WX	39773
IgG	Patient 3	4	mild	G19118WX	38239
IgM	Patient 3	11	mild	G19118WX	9095
IgM	Patient 3	4	mild	G19118WX	9756
IgA	Patient 4	12	mild	G19118WX	395
IgG	Patient 4	12	mild	G19118WX	463
IgM	Patient 4	12	mild	G19118WX	162
IgA	Patient 1	10	moderate	G19868AX	376
IgA	Patient 1	22	moderate	G19868AX	298
IgA	Patient 1	6	moderate	G19868AX	360
IgG	Patient 1	10	moderate	G19868AX	23
IgG	Patient 1	22	moderate	G19868AX	29
IgG	Patient 1	6	moderate	G19868AX	27
IgM	Patient 1	10	moderate	G19868AX	44
IgM	Patient 1	22	moderate	G19868AX	122
IgM	Patient 1	6	moderate	G19868AX	53
IgA	Patient 2	15	mild	G19868AX	346