GlyCosmos Portal

GlyCOVID

GlyCOVID is a dataset of RDFized COVID-19 data related to glycans. Resources will be added incrementally as publications are curated.

Longitudinal Development of Antibody Responses in COVID-19 Patients of Different Severity with ELISA, Peptide, and Glycan Arrays: An Immunological Case Series.
Heidepriem J, et al.
Pathogens. 2021; 10(4):438. https://doi.org/10.3390/pathogens10040438

A longitudinal analysis of three COVID-19 patients with moderate (#1) and mild disease (#2 and #3) was published. Antibody serum responses were analyzed using spike glycoprotein enzyme linked immunosorbent assay (ELISA), full-proteome peptide, and glycan microarrays. In this Glycovid dataset, the data from these glycan microarray experiments have been RDFized. Fluorescence intensity is given in arbitrary fluorescence units (AFU) as reported in this publication.

Source	Last Updated
PSICQUIC	March 30, 2022

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Antibody	Patient	Onset (days)	Symptom	GlyTouCan ID ▲	Arbitrary Fluorescence Units (AFU)
IgG	Patient 3	-180	mild	G21460SG	46
IgM	Patient 3	-180	mild	G21460SG	93
IgA	Patient 3	4	mild	G21460SG	506
IgG	Patient 3	11	mild	G21460SG	99
IgG	Patient 3	4	mild	G21460SG	88
IgM	Patient 3	11	mild	G21460SG	92
IgM	Patient 3	4	mild	G21460SG	77
IgA	Patient 4	12	mild	G21460SG	386
IgG	Patient 4	12	mild	G21460SG	74
IgM	Patient 4	12	mild	G21460SG	163
IgA	Patient 1	10	moderate	G21675ZL	339
IgA	Patient 1	22	moderate	G21675ZL	398
IgA	Patient 1	6	moderate	G21675ZL	393
IgG	Patient 1	10	moderate	G21675ZL	28
IgG	Patient 1	22	moderate	G21675ZL	36
IgG	Patient 1	6	moderate	G21675ZL	32
IgM	Patient 1	10	moderate	G21675ZL	48
IgM	Patient 1	22	moderate	G21675ZL	101
IgM	Patient 1	6	moderate	G21675ZL	46
IgA	Patient 2	15	mild	G21675ZL	1530
IgA	Patient 2	24	mild	G21675ZL	2502
IgG	Patient 2	15	mild	G21675ZL	974
IgG	Patient 2	24	mild	G21675ZL	1600
IgM	Patient 2	15	mild	G21675ZL	1532
IgM	Patient 2	24	mild	G21675ZL	3212