GlyCosmos Portal

GlyCOVID

GlyCOVID is a dataset of RDFized COVID-19 data related to glycans. Resources will be added incrementally as publications are curated.

Longitudinal Development of Antibody Responses in COVID-19 Patients of Different Severity with ELISA, Peptide, and Glycan Arrays: An Immunological Case Series.
Heidepriem J, et al.
Pathogens. 2021; 10(4):438. https://doi.org/10.3390/pathogens10040438

A longitudinal analysis of three COVID-19 patients with moderate (#1) and mild disease (#2 and #3) was published. Antibody serum responses were analyzed using spike glycoprotein enzyme linked immunosorbent assay (ELISA), full-proteome peptide, and glycan microarrays. In this Glycovid dataset, the data from these glycan microarray experiments have been RDFized. Fluorescence intensity is given in arbitrary fluorescence units (AFU) as reported in this publication.

Source	Last Updated
PSICQUIC	March 30, 2022

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Antibody	Patient	Onset (days)	Symptom	GlyTouCan ID ▲	Arbitrary Fluorescence Units (AFU)
IgA	Patient 2	3	mild	G21675ZL	1838
IgG	Patient 2	3	mild	G21675ZL	1378
IgM	Patient 2	3	mild	G21675ZL	1242
IgA	Patient 3	-180	mild	G21675ZL	382
IgA	Patient 3	11	mild	G21675ZL	520
IgG	Patient 3	-180	mild	G21675ZL	83
IgM	Patient 3	-180	mild	G21675ZL	398
IgA	Patient 3	4	mild	G21675ZL	495
IgG	Patient 3	11	mild	G21675ZL	104
IgG	Patient 3	4	mild	G21675ZL	86
IgM	Patient 3	11	mild	G21675ZL	539
IgM	Patient 3	4	mild	G21675ZL	452
IgA	Patient 4	12	mild	G21675ZL	488
IgG	Patient 4	12	mild	G21675ZL	108
IgM	Patient 4	12	mild	G21675ZL	551
IgA	Patient 1	10	moderate	G22768VO	368
IgA	Patient 1	22	moderate	G22768VO	416
IgA	Patient 1	6	moderate	G22768VO	327
IgG	Patient 1	10	moderate	G22768VO	29
IgG	Patient 1	22	moderate	G22768VO	42
IgG	Patient 1	6	moderate	G22768VO	27
IgM	Patient 1	10	moderate	G22768VO	52
IgM	Patient 1	22	moderate	G22768VO	192
IgM	Patient 1	6	moderate	G22768VO	47
IgA	Patient 2	15	mild	G22768VO	984