GlyCosmos Portal

GlyCOVID

GlyCOVID is a dataset of RDFized COVID-19 data related to glycans. Resources will be added incrementally as publications are curated.

Longitudinal Development of Antibody Responses in COVID-19 Patients of Different Severity with ELISA, Peptide, and Glycan Arrays: An Immunological Case Series.
Heidepriem J, et al.
Pathogens. 2021; 10(4):438. https://doi.org/10.3390/pathogens10040438

A longitudinal analysis of three COVID-19 patients with moderate (#1) and mild disease (#2 and #3) was published. Antibody serum responses were analyzed using spike glycoprotein enzyme linked immunosorbent assay (ELISA), full-proteome peptide, and glycan microarrays. In this Glycovid dataset, the data from these glycan microarray experiments have been RDFized. Fluorescence intensity is given in arbitrary fluorescence units (AFU) as reported in this publication.

Source	Last Updated
PSICQUIC	March 30, 2022

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Antibody	Patient	Onset (days)	Symptom	GlyTouCan ID ▲	Arbitrary Fluorescence Units (AFU)
IgG	Patient 1	6	moderate	G24432YB	24
IgM	Patient 1	10	moderate	G24432YB	28
IgM	Patient 1	22	moderate	G24432YB	28
IgM	Patient 1	6	moderate	G24432YB	26
IgA	Patient 2	15	mild	G24432YB	221
IgA	Patient 2	24	mild	G24432YB	284
IgG	Patient 2	15	mild	G24432YB	23
IgG	Patient 2	24	mild	G24432YB	28
IgM	Patient 2	15	mild	G24432YB	35
IgM	Patient 2	24	mild	G24432YB	46
IgA	Patient 2	3	mild	G24432YB	247
IgG	Patient 2	3	mild	G24432YB	24
IgM	Patient 2	3	mild	G24432YB	40
IgA	Patient 3	-180	mild	G24432YB	260
IgA	Patient 3	11	mild	G24432YB	306
IgG	Patient 3	-180	mild	G24432YB	48
IgM	Patient 3	-180	mild	G24432YB	81
IgA	Patient 3	4	mild	G24432YB	413
IgG	Patient 3	11	mild	G24432YB	45
IgG	Patient 3	4	mild	G24432YB	51
IgM	Patient 3	11	mild	G24432YB	94
IgM	Patient 3	4	mild	G24432YB	123
IgA	Patient 4	12	mild	G24432YB	428
IgG	Patient 4	12	mild	G24432YB	118
IgM	Patient 4	12	mild	G24432YB	321