GlyCosmos Portal

GlyCOVID

GlyCOVID is a dataset of RDFized COVID-19 data related to glycans. Resources will be added incrementally as publications are curated.

Longitudinal Development of Antibody Responses in COVID-19 Patients of Different Severity with ELISA, Peptide, and Glycan Arrays: An Immunological Case Series.
Heidepriem J, et al.
Pathogens. 2021; 10(4):438. https://doi.org/10.3390/pathogens10040438

A longitudinal analysis of three COVID-19 patients with moderate (#1) and mild disease (#2 and #3) was published. Antibody serum responses were analyzed using spike glycoprotein enzyme linked immunosorbent assay (ELISA), full-proteome peptide, and glycan microarrays. In this Glycovid dataset, the data from these glycan microarray experiments have been RDFized. Fluorescence intensity is given in arbitrary fluorescence units (AFU) as reported in this publication.

Source	Last Updated
PSICQUIC	March 30, 2022

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Antibody	Patient	Onset (days)	Symptom	GlyTouCan ID ▲	Arbitrary Fluorescence Units (AFU)
IgG	Patient 1	6	moderate	G26125KY	114
IgM	Patient 1	10	moderate	G26125KY	32
IgM	Patient 1	22	moderate	G26125KY	34
IgM	Patient 1	6	moderate	G26125KY	34
IgA	Patient 2	15	mild	G26125KY	461
IgA	Patient 2	24	mild	G26125KY	521
IgG	Patient 2	15	mild	G26125KY	14323
IgG	Patient 2	24	mild	G26125KY	13804
IgM	Patient 2	15	mild	G26125KY	236
IgM	Patient 2	24	mild	G26125KY	259
IgA	Patient 2	3	mild	G26125KY	634
IgG	Patient 2	3	mild	G26125KY	26641
IgM	Patient 2	3	mild	G26125KY	394
IgA	Patient 3	-180	mild	G26125KY	2520
IgA	Patient 3	11	mild	G26125KY	2531
IgG	Patient 3	-180	mild	G26125KY	1382
IgM	Patient 3	-180	mild	G26125KY	7474
IgA	Patient 3	4	mild	G26125KY	2601
IgG	Patient 3	11	mild	G26125KY	1785
IgG	Patient 3	4	mild	G26125KY	1842
IgM	Patient 3	11	mild	G26125KY	7852
IgM	Patient 3	4	mild	G26125KY	8060
IgA	Patient 4	12	mild	G26125KY	459
IgG	Patient 4	12	mild	G26125KY	285
IgM	Patient 4	12	mild	G26125KY	151