GlyCosmos Portal

GlyCOVID

GlyCOVID is a dataset of RDFized COVID-19 data related to glycans. Resources will be added incrementally as publications are curated.

Longitudinal Development of Antibody Responses in COVID-19 Patients of Different Severity with ELISA, Peptide, and Glycan Arrays: An Immunological Case Series.
Heidepriem J, et al.
Pathogens. 2021; 10(4):438. https://doi.org/10.3390/pathogens10040438

A longitudinal analysis of three COVID-19 patients with moderate (#1) and mild disease (#2 and #3) was published. Antibody serum responses were analyzed using spike glycoprotein enzyme linked immunosorbent assay (ELISA), full-proteome peptide, and glycan microarrays. In this Glycovid dataset, the data from these glycan microarray experiments have been RDFized. Fluorescence intensity is given in arbitrary fluorescence units (AFU) as reported in this publication.

Source	Last Updated
PSICQUIC	March 30, 2022

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Antibody	Patient	Onset (days)	Symptom	GlyTouCan ID ▲	Arbitrary Fluorescence Units (AFU)
IgA	Patient 1	10	moderate	G26295XE	371
IgA	Patient 1	22	moderate	G26295XE	320
IgA	Patient 1	6	moderate	G26295XE	390
IgG	Patient 1	10	moderate	G26295XE	25
IgG	Patient 1	22	moderate	G26295XE	30
IgG	Patient 1	6	moderate	G26295XE	25
IgM	Patient 1	10	moderate	G26295XE	31
IgM	Patient 1	22	moderate	G26295XE	80
IgM	Patient 1	6	moderate	G26295XE	32
IgA	Patient 2	15	mild	G26295XE	329
IgA	Patient 2	24	mild	G26295XE	369
IgG	Patient 2	15	mild	G26295XE	1950
IgG	Patient 2	24	mild	G26295XE	1657
IgM	Patient 2	15	mild	G26295XE	127
IgM	Patient 2	24	mild	G26295XE	129
IgA	Patient 2	3	mild	G26295XE	368
IgG	Patient 2	3	mild	G26295XE	2574
IgM	Patient 2	3	mild	G26295XE	178
IgA	Patient 3	-180	mild	G26295XE	1428
IgA	Patient 3	11	mild	G26295XE	1839
IgG	Patient 3	-180	mild	G26295XE	451
IgM	Patient 3	-180	mild	G26295XE	3839
IgA	Patient 3	4	mild	G26295XE	1687
IgG	Patient 3	11	mild	G26295XE	877
IgG	Patient 3	4	mild	G26295XE	810