GlyCosmos Portal

GlyCOVID

GlyCOVID is a dataset of RDFized COVID-19 data related to glycans. Resources will be added incrementally as publications are curated.

Longitudinal Development of Antibody Responses in COVID-19 Patients of Different Severity with ELISA, Peptide, and Glycan Arrays: An Immunological Case Series.
Heidepriem J, et al.
Pathogens. 2021; 10(4):438. https://doi.org/10.3390/pathogens10040438

A longitudinal analysis of three COVID-19 patients with moderate (#1) and mild disease (#2 and #3) was published. Antibody serum responses were analyzed using spike glycoprotein enzyme linked immunosorbent assay (ELISA), full-proteome peptide, and glycan microarrays. In this Glycovid dataset, the data from these glycan microarray experiments have been RDFized. Fluorescence intensity is given in arbitrary fluorescence units (AFU) as reported in this publication.

Source	Last Updated
PSICQUIC	March 30, 2022

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Antibody	Patient	Onset (days)	Symptom	GlyTouCan ID ▲	Arbitrary Fluorescence Units (AFU)
IgG	Patient 3	-180	mild	G27689OB	40
IgM	Patient 3	-180	mild	G27689OB	57
IgA	Patient 3	4	mild	G27689OB	447
IgG	Patient 3	11	mild	G27689OB	341
IgG	Patient 3	4	mild	G27689OB	306
IgM	Patient 3	11	mild	G27689OB	119
IgM	Patient 3	4	mild	G27689OB	108
IgA	Patient 4	12	mild	G27689OB	377
IgG	Patient 4	12	mild	G27689OB	52
IgM	Patient 4	12	mild	G27689OB	117
IgA	Patient 1	10	moderate	G28868ZC	346
IgA	Patient 1	22	moderate	G28868ZC	291
IgA	Patient 1	6	moderate	G28868ZC	319
IgG	Patient 1	10	moderate	G28868ZC	23
IgG	Patient 1	22	moderate	G28868ZC	21
IgG	Patient 1	6	moderate	G28868ZC	23
IgM	Patient 1	10	moderate	G28868ZC	31
IgM	Patient 1	22	moderate	G28868ZC	29
IgM	Patient 1	6	moderate	G28868ZC	29
IgA	Patient 2	15	mild	G28868ZC	229
IgA	Patient 2	24	mild	G28868ZC	275
IgG	Patient 2	15	mild	G28868ZC	24
IgG	Patient 2	24	mild	G28868ZC	24
IgM	Patient 2	15	mild	G28868ZC	33
IgM	Patient 2	24	mild	G28868ZC	39