GlyCosmos Portal

GlyCOVID

GlyCOVID is a dataset of RDFized COVID-19 data related to glycans. Resources will be added incrementally as publications are curated.

Longitudinal Development of Antibody Responses in COVID-19 Patients of Different Severity with ELISA, Peptide, and Glycan Arrays: An Immunological Case Series.
Heidepriem J, et al.
Pathogens. 2021; 10(4):438. https://doi.org/10.3390/pathogens10040438

A longitudinal analysis of three COVID-19 patients with moderate (#1) and mild disease (#2 and #3) was published. Antibody serum responses were analyzed using spike glycoprotein enzyme linked immunosorbent assay (ELISA), full-proteome peptide, and glycan microarrays. In this Glycovid dataset, the data from these glycan microarray experiments have been RDFized. Fluorescence intensity is given in arbitrary fluorescence units (AFU) as reported in this publication.

Source	Last Updated
PSICQUIC	March 30, 2022

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Antibody	Patient	Onset (days)	Symptom	GlyTouCan ID ▲	Arbitrary Fluorescence Units (AFU)
IgA	Patient 2	3	mild	G28868ZC	250
IgG	Patient 2	3	mild	G28868ZC	25
IgM	Patient 2	3	mild	G28868ZC	38
IgA	Patient 3	-180	mild	G28868ZC	232
IgA	Patient 3	11	mild	G28868ZC	374
IgG	Patient 3	-180	mild	G28868ZC	39
IgM	Patient 3	-180	mild	G28868ZC	68
IgA	Patient 3	4	mild	G28868ZC	395
IgG	Patient 3	11	mild	G28868ZC	46
IgG	Patient 3	4	mild	G28868ZC	44
IgM	Patient 3	11	mild	G28868ZC	122
IgM	Patient 3	4	mild	G28868ZC	128
IgA	Patient 4	12	mild	G28868ZC	348
IgG	Patient 4	12	mild	G28868ZC	98
IgM	Patient 4	12	mild	G28868ZC	153
IgA	Patient 1	10	moderate	G29011JC	385
IgA	Patient 1	22	moderate	G29011JC	405
IgA	Patient 1	6	moderate	G29011JC	387
IgG	Patient 1	10	moderate	G29011JC	26
IgG	Patient 1	22	moderate	G29011JC	39
IgG	Patient 1	6	moderate	G29011JC	27
IgM	Patient 1	10	moderate	G29011JC	46
IgM	Patient 1	22	moderate	G29011JC	172
IgM	Patient 1	6	moderate	G29011JC	40
IgA	Patient 2	15	mild	G29011JC	504