GlyCosmos Portal

GlyCOVID

GlyCOVID is a dataset of RDFized COVID-19 data related to glycans. Resources will be added incrementally as publications are curated.

Longitudinal Development of Antibody Responses in COVID-19 Patients of Different Severity with ELISA, Peptide, and Glycan Arrays: An Immunological Case Series.
Heidepriem J, et al.
Pathogens. 2021; 10(4):438. https://doi.org/10.3390/pathogens10040438

A longitudinal analysis of three COVID-19 patients with moderate (#1) and mild disease (#2 and #3) was published. Antibody serum responses were analyzed using spike glycoprotein enzyme linked immunosorbent assay (ELISA), full-proteome peptide, and glycan microarrays. In this Glycovid dataset, the data from these glycan microarray experiments have been RDFized. Fluorescence intensity is given in arbitrary fluorescence units (AFU) as reported in this publication.

Source	Last Updated
PSICQUIC	March 30, 2022

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Antibody	Patient	Onset (days)	Symptom	GlyTouCan ID ▲	Arbitrary Fluorescence Units (AFU)
IgM	Patient 3	11	mild	G30839DN	164
IgM	Patient 3	4	mild	G30839DN	166
IgA	Patient 4	12	mild	G30839DN	463
IgG	Patient 4	12	mild	G30839DN	552
IgM	Patient 4	12	mild	G30839DN	168
IgA	Patient 1	10	moderate	G31265MS	408
IgA	Patient 1	22	moderate	G31265MS	420
IgA	Patient 1	6	moderate	G31265MS	355
IgG	Patient 1	10	moderate	G31265MS	25
IgG	Patient 1	22	moderate	G31265MS	36
IgG	Patient 1	6	moderate	G31265MS	23
IgM	Patient 1	10	moderate	G31265MS	50
IgM	Patient 1	22	moderate	G31265MS	176
IgM	Patient 1	6	moderate	G31265MS	54
IgA	Patient 2	15	mild	G31265MS	396
IgA	Patient 2	24	mild	G31265MS	420
IgG	Patient 2	15	mild	G31265MS	975
IgG	Patient 2	24	mild	G31265MS	859
IgM	Patient 2	15	mild	G31265MS	182
IgM	Patient 2	24	mild	G31265MS	202
IgA	Patient 2	3	mild	G31265MS	456
IgG	Patient 2	3	mild	G31265MS	1728
IgM	Patient 2	3	mild	G31265MS	307
IgA	Patient 3	-180	mild	G31265MS	247
IgA	Patient 3	11	mild	G31265MS	423