GlyCosmos Portal

GlyCOVID

GlyCOVID is a dataset of RDFized COVID-19 data related to glycans. Resources will be added incrementally as publications are curated.

Longitudinal Development of Antibody Responses in COVID-19 Patients of Different Severity with ELISA, Peptide, and Glycan Arrays: An Immunological Case Series.
Heidepriem J, et al.
Pathogens. 2021; 10(4):438. https://doi.org/10.3390/pathogens10040438

A longitudinal analysis of three COVID-19 patients with moderate (#1) and mild disease (#2 and #3) was published. Antibody serum responses were analyzed using spike glycoprotein enzyme linked immunosorbent assay (ELISA), full-proteome peptide, and glycan microarrays. In this Glycovid dataset, the data from these glycan microarray experiments have been RDFized. Fluorescence intensity is given in arbitrary fluorescence units (AFU) as reported in this publication.

Source	Last Updated
PSICQUIC	March 30, 2022

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Antibody	Patient	Onset (days)	Symptom	GlyTouCan ID ▲	Arbitrary Fluorescence Units (AFU)
IgM	Patient 3	11	mild	G00057MO	1910
IgM	Patient 3	4	mild	G00057MO	2028
IgA	Patient 4	12	mild	G00057MO	800
IgG	Patient 4	12	mild	G00057MO	215
IgM	Patient 4	12	mild	G00057MO	1468
IgA	Patient 1	10	moderate	G00065MO	432
IgA	Patient 1	22	moderate	G00065MO	364
IgA	Patient 1	6	moderate	G00065MO	381
IgG	Patient 1	10	moderate	G00065MO	26
IgG	Patient 1	22	moderate	G00065MO	27
IgG	Patient 1	6	moderate	G00065MO	27
IgM	Patient 1	10	moderate	G00065MO	41
IgM	Patient 1	22	moderate	G00065MO	58
IgM	Patient 1	6	moderate	G00065MO	42
IgA	Patient 2	15	mild	G00065MO	267
IgA	Patient 2	24	mild	G00065MO	291
IgG	Patient 2	15	mild	G00065MO	57
IgG	Patient 2	24	mild	G00065MO	25
IgM	Patient 2	15	mild	G00065MO	75
IgM	Patient 2	24	mild	G00065MO	45
IgA	Patient 2	3	mild	G00065MO	265
IgG	Patient 2	3	mild	G00065MO	25
IgM	Patient 2	3	mild	G00065MO	42
IgA	Patient 3	-180	mild	G00065MO	293
IgA	Patient 3	11	mild	G00065MO	396