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B-cell receptor CD22

Summary

Organism: Homo sapiens (human)

External Links

UniProt: P20273
UniLectin: P20273

Annotation

Keyword

3D-structure
Alternative splicing
Cell adhesion
Cell membrane
Disulfide bond
Glycoprotein
Immunoglobulin domain
Isopeptide bond
Lectin
Phosphoprotein
Reference proteome
Repeat
Signal
Transmembrane helix

Gene Ontology (GO)

Displaying **all 8** entries
GO Term
negative regulation of immunoglobulin production
cell adhesion
regulation of endocytosis
regulation of B cell proliferation
B cell activation
regulation of immune response
negative regulation of B cell receptor signaling pathway
negative regulation of calcium-mediated signaling

Displaying **all 9** entries
GO Term
early endosome
external side of plasma membrane
cell surface
cytoplasm
plasma membrane
membrane
neuronal cell body membrane
recycling endosome
extracellular exosome

Displaying **all 6** entries
GO Term
signaling receptor binding
carbohydrate binding
protein phosphatase binding
sialic acid binding
CD4 receptor binding
IgM binding

Annotation information from UniProt.

Pathway

Displaying **all 3** entries
Pathway Name	Organism
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers	Homo sapiens
CD22 mediated BCR regulation	Homo sapiens
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	Homo sapiens

UniLectin

UniProt	PDB
P20273	5VKJ 5VKM

MCAW-DB (Glycan Recognition Profile)

MCAW-DB is a database whereby users can view the multiple alignment analysis results obtained from the MCAW tool, which can computationally find common glycan substructures among a group of glycan structures. The data in MCAW-DB are analysis results of glycan array experiments; those glycans having higher binding affinity to glycan binding proteins (GBPs) have been analyzed and can be viewed as “glycan recognition profiles”. Currently, this database provides published analysis results of glycan array data from the Consortium for Functional Glycomics (CFG).