GlyCosmos Portal

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Galectin-1

Summary

Lectin Name Aliases

Galectin-1

Organism

Homo sapiens (human)

External Links

UniProt

P09382

LfDB

LfDB0270

UniLectin

P09382

CarboGrove

1024

Annotation

Keyword

3D-structure
Acetylation
Apoptosis
Cytoplasm
Direct protein sequencing
Extracellular matrix
Lectin
Phosphoprotein
Reference proteome

Gene Ontology (GO)

Displaying **all 10** entries
GO Term
apoptotic process
regulation of apoptotic process
positive regulation of apoptotic process
positive regulation of inflammatory response
cell-cell adhesion
plasma cell differentiation
positive regulation of viral entry into host cell
T cell costimulation
positive regulation of canonical NF-kappaB signal transduction
myoblast differentiation

Displaying **all 8** entries
GO Term
endoplasmic reticulum lumen
cytosol
extracellular region
extracellular space
cytoplasm
collagen-containing extracellular matrix
galectin complex
extracellular exosome

Displaying **all 4** entries
GO Term
galactoside binding
laminin binding
lactose binding
RNA binding

Annotation information from UniProt.

Pathway

Displaying **all 2** entries
Pathway Name	Organism
Post-translational protein phosphorylation	Homo sapiens
Regulation of IGF Activity by IGFBP	Homo sapiens

UniLectin

UniProt	PDB
P09382	1GZW 1W6M 1W6N 1W6O 1W6P 1W6Q 2KM2 2ZKN 3OY8 3OYW 3T2T 3W58 3W59 4Q1P 4Q1R 4Q26 4Q27 4Q2F 4XBL 4Y1U 4Y1V 4Y1X 4Y1Y 4Y1Z 4Y20 4Y22 4Y24 5MWT 5MWX 6B94 6F83

CarboGrove

Lectin Name: Human Galectin 1
Common Name: Gal 1

Automated Analysis report (Top 10 high affinity glycans)

Array Source

ASNLinked

Protein Source

Investigator Provided

Concentration (ug/mL)

GlyTouCan ID	Binding Intensity	Stdev
G03652TR	131.5	24.6779
G63889NK	127.5	26.1598
G28800UK	124.5	56.205
G73866ZM	119.5	28.8733
G72506RN	118.5	75.6373
G66741YQ	115.25	94.4012
G18938DW	108.5	88.775
G45359RY	71.0	6.6833
G79809MM	49.75	18.4097
G78030KJ	32.5	27.037

GlyTouCan ID	Binding Intensity	Stdev
G18938DW	1893.5	141.531
G86357DX	1579.25	408.956
G63889NK	1545.75	144.232
G66741YQ	1098.25	106.24
G29857RC	1063.75	348.49
G45359RY	1005.5	155.796
G79809MM	1001.75	61.9106
G78059CC	947.5	123.948
G03652TR	645.75	52.3601
G36191CD	555.0	103.605

CarboGrove View

MCAW-DB (Glycan Recognition Profile)

MCAW-DB is a database whereby users can view the multiple alignment analysis results obtained from the MCAW tool, which can computationally find common glycan substructures among a group of glycan structures. The data in MCAW-DB are analysis results of glycan array experiments; those glycans having higher binding affinity to glycan binding proteins (GBPs) have been analyzed and can be viewed as “glycan recognition profiles”. Currently, this database provides published analysis results of glycan array data from the Consortium for Functional Glycomics (CFG).