GlyCosmos Portal

Submissions

Complement C4-B

Summary

Organism: Homo sapiens (human)

External Links

UniProt: P0C0L5

Annotation

Keyword

3D-structure
Blood group antigen
Cell projection
Cleavage on pair of basic residues
Complement pathway
Direct protein sequencing
Disulfide bond
Glycoprotein
Inflammatory response
Phosphoprotein
Reference proteome
Secreted
Signal
Sulfation
Synapse
Systemic lupus erythematosus
Thioester bond

Gene Ontology (GO)

Displaying **all 7** entries
GO Term
inflammatory response
complement activation
innate immune response
complement activation, classical pathway
opsonization
detection of molecule of bacterial origin
positive regulation of apoptotic cell clearance

Displaying **all 9** entries
GO Term
extracellular region
extracellular space
plasma membrane
axon
dendrite
synapse
extracellular exosome
blood microparticle
symbiont cell surface

Displaying **all 3** entries
GO Term
carbohydrate binding
endopeptidase inhibitor activity
complement binding

Annotation information from UniProt.

Pathway

Displaying **all 3** entries
Pathway Name	Organism
Activation of C3 and C5	Homo sapiens
Initial triggering of complement	Homo sapiens
Regulation of Complement cascade	Homo sapiens

MCAW-DB (Glycan Recognition Profile)

MCAW-DB is a database whereby users can view the multiple alignment analysis results obtained from the MCAW tool, which can computationally find common glycan substructures among a group of glycan structures. The data in MCAW-DB are analysis results of glycan array experiments; those glycans having higher binding affinity to glycan binding proteins (GBPs) have been analyzed and can be viewed as “glycan recognition profiles”. Currently, this database provides published analysis results of glycan array data from the Consortium for Functional Glycomics (CFG).