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MIRAGE
Leucoagglutinating phytohemagglutinin

Summary
Lectin Name Aliases
  • PHA-L
  • Phaseolus Vulgaris Leucoagglutinin
Monosaccharide Specificities
  • GalNAc
Organism
Phaseolus vulgaris
UniProt
P05087
LfDB
UniLectin
P05087
CarboGrove
Annotation
Keyword
  • 3D-structure
  • Glycoprotein
  • Mannose-binding
  • Plant defense
  • Signal
  • Toxin
Gene Ontology (GO)
Displaying 1 entry
GO Term
defense response
Displaying all 2 entries
GO Term
mannose binding
toxin activity
Annotation information from UniProt.
Reference
Displaying all 3 entries
PubMed ID Title First Author
8130390 Mutation of Asn128 to Asp of Phaseolus vulgaris leucoagglutinin (PHA-L) eliminates carbohydrate-binding and biological activity. Mirkov TE
8702788 The crystallographic structure of phytohemagglutinin-L. Hamelryck TW
10561459 Glycosylation alterations of cells in late phase apoptosis from colon carcinomas. Rapoport E
Lectin Frontier DataBase (LfDB)
GlyTouCan
G07669FN
V-V0
28.11
GlyTouCan
G55828KH
V-V0
27.91
GlyTouCan
G86157UQ
V-V0
26.84
LfDB provides quantitative interaction data in terms of the affinity constants (Ka) of a series of lectins toward a panel of pyridylaminated (PA) glycans obtained by an automated frontal affinity chromatography with fluorescence detection (FAC-FD) system. Since the data are accurate and reliable, providing the absolute values of sugar-protein interactions, LfDB would be a valuable resource in the studies of glycan-related biology.
MCAW
The MCAW profile of the top three glycans above, which resulted from FAC analysis.
UniLectin
UniProt
P05087
CarboGrove
Lectin Name
Phaseolus Vulgaris Leucoagglutinin
Common Name
PHA-L
Automated Analysis report (Top 10 high affinity glycans)
Array Source
ASNLinked
Protein Source
Vector
Concentration (ug/mL)

GlyTouCan ID Binding Intensity Stdev
G94531EZ
12737 2577
G63889NK
12703 818
G18938DW
12046 782
G45209NR
11522 424
G56318NV
9796 266
G98366ZJ
9725 2327
G79809MM
8642 545
G45359RY
8242 959
G39018CC
46 41
G20030CU
37 1

GlyTouCan ID Binding Intensity Stdev
G18938DW
16805.25 500.64
G56318NV
16729.75 537.46
G79809MM
15719.25 3402.94
G94531EZ
15637 3607.26
G63889NK
13525 3278.72
G45209NR
13483 3624.95
G45359RY
11306.75 3197.29
G98366ZJ
9141.5 429.46
G66741YQ
123 25.52
G20030CU
62 10.23
CarboGrove View
Array Source
CFG
Protein Source
Vector
Concentration (ug/mL)

GlyTouCan ID Binding Intensity Stdev
G91827TX
376.99 19.66
G58956TM
337.4 92.3
G35679TE
312.81 15.67
G45359RY
278.11 32.77
G19687OL
226.72 31.31
G17807LO
197.1 54.39
G64586PM
177.66 41.5
G88094DN
170.59 70.42
G18988VX
169.79 17.42
G06714AG
167.35 14.66

GlyTouCan ID Binding Intensity Stdev
G91827TX
6710.21 304.52
G58956TM
5331.88 428.9
G35679TE
4799.35 639.74
G45359RY
4505.51 297.96
G17807LO
4147.99 457.74
G88094DN
4093.34 293.58
G09713JE
2439.88 308.98
G17779DH
2123.26 97.4
G95492XR
1989.17 268.27
G57604VY
1932.56 291.82

GlyTouCan ID Binding Intensity Stdev
G35679TE
22612.98 1375.27
G91827TX
22219.51 1069.78
G58956TM
21513.89 449.69
G45359RY
19902.46 1365.75
G88094DN
18585.27 947.08
G17807LO
17778.37 1735.61
G09713JE
17480.27 644.97
G80313NY
13297.76 142.96
G55718HL
13063.24 540.87
G57604VY
12741.92 282.55

GlyTouCan ID Binding Intensity Stdev
G58956TM
29388.95 3181.67
G88094DN
29372.23 1704.36
G45359RY
27672.28 1122.04
G35679TE
26364.29 2765.98
G59122OR
24957.64 1363.96
G80313NY
24453.53 1097.03
G83133GQ
23777.07 682.18
G97894QD
23112.85 562.57
G55718HL
22701.95 849.08
G91827TX
22495.79 1428.02
CarboGrove View
Array Source
NCFG
Protein Source
Vector
Concentration (ug/mL)

GlyTouCan ID Binding Intensity Stdev
G58956TM
13843 1034
G95492XR
10838 330
G45359RY
10069 831
G88094DN
8044 3253
G97894QD
8012 213
G35679TE
7953 1095
G09713JE
7737 177
G57604VY
6918 313
G55718HL
6619 906
G83133GQ
6076 290

GlyTouCan ID Binding Intensity Stdev
G95492XR
54096 10555
G57604VY
53955 5915
G58956TM
50456 5706
G59122OR
43620 1591
G09713JE
43615 6407
G83133GQ
38898 2477
G97894QD
37483 6991
G96852SM
35110 1380
G80313NY
33640 6389
G45359RY
33620 2388
CarboGrove View
Array Source
ZBiotech
Protein Source
Vector
Concentration (ug/mL)

GlyTouCan ID Binding Intensity Stdev
G86522OD
4756.5 0
G76241TN
651.67 0
G96896RL
407.67 0
G29024OJ
173.33 0
G74353FF
106.5 0
G24604HV
80 0
G66741YQ
68 0
G88495BI
61.33 0
G98173LG
51.33 0
G88313DY
38.33 0
CarboGrove View
CarboGrove is populated with the results from 35 types of glycan arrays, 13 glycan families, 5 experimental methods, and 19 laboratories or companies by processing and interpreting data from various types of glycan arrays.
PDB
1FAT
© PDBj クリエイティブ・コモンズ 表示 4.0 国際 ライセンス
1G8W
© PDBj クリエイティブ・コモンズ 表示 4.0 国際 ライセンス
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025