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Mannose-binding protein C

Summary

Organism: Homo sapiens (human)

External Links

UniProt: P11226
UniLectin: P11226

Annotation

Keyword

3D-structure
Calcium
Coiled coil
Collagen
Complement activation lectin pathway
Complement pathway
Direct protein sequencing
Disulfide bond
Hydroxylation
Mannose-binding
Reference proteome
Repeat
Secreted
Signal

Gene Ontology (GO)

Displaying entries **1 - 10** of 16 in total

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GO Term
defense response to Gram-positive bacterium
proteolysis
defense response to bacterium
surfactant homeostasis
innate immune response
positive regulation of phagocytosis
killing by host of symbiont cells
opsonization
negative regulation of viral process
positive regulation of opsonization

Displaying **all 7** entries
GO Term
external side of plasma membrane
cell surface
extracellular region
collagen trimer
extracellular space
serine-type endopeptidase complex
multivesicular body

Displaying **all 4** entries
GO Term
signaling receptor binding
mannose binding
identical protein binding
calcium-dependent protein binding

Annotation information from UniProt.

Pathway

Displaying **all 3** entries
Pathway Name	Organism
Initial triggering of complement	Homo sapiens
Lectin pathway of complement activation	Homo sapiens
SARS-CoV-2 activates/modulates innate and adaptive immune responses	Homo sapiens

UniLectin

UniProt	PDB
P11226	1HUP

MCAW-DB (Glycan Recognition Profile)

1641

MCAW-DB is a database whereby users can view the multiple alignment analysis results obtained from the MCAW tool, which can computationally find common glycan substructures among a group of glycan structures. The data in MCAW-DB are analysis results of glycan array experiments; those glycans having higher binding affinity to glycan binding proteins (GBPs) have been analyzed and can be viewed as “glycan recognition profiles”. Currently, this database provides published analysis results of glycan array data from the Consortium for Functional Glycomics (CFG).